KTE100184 | Rat Trypsinogen activation peptide (TAP) ELISA Kit — The Early Warning Biomarker for Acute Pancreatitis in Rat Models
TAP: The Molecular Signature of Premature Trypsinogen Activation Trypsinogen-activation peptide (TAP) is a small peptide released when trypsinogen is activated to trypsin[reference:123]. Under physiological conditions, trypsinogen activation occurs in the intestinal lumen and is catalyzed by enteropeptidase[reference:124]. However, in acute pancreatitis, trypsinogen is prematurely activated within the pancreas itself—releasing TAP into the circulation and urine. TAP is an established early biomarker for acute pancreatitis, with elevated levels correlating with the severity of pancreatic injury. In rat models, TAP quantification is essential for studying pancreatitis pathogenesis and evaluating potential therapeutics. The Rat Trypsinogen activation peptide (TAP) ELISA Kit (KTE100184) delivers precise, reproducible TAP measurement. Sandwich ELISA: Dual-Antibody Capture for Pancreatic-Specific Detection This kit employs a two-site sandwich ELISA to quantitate TAP…
KTE100170 | Rat Thyroxine (T4) ELISA Kit — Quantifying the Thyroid‘s Primary Secretory Product in Rat Models
T4: The Thyroid‘s Workhorse Hormone Thyroxine (T4) is the principal hormone secreted by the thyroid gland—accounting for the vast majority of thyroid hormone output. In normal thyroid function, total T4 levels parallel thyroid status: hyperthyroidism is characterized by increased circulating T4, hypothyroidism by decreased levels[reference:104]. However, exceptions exist: TBG levels are altered under various physiological, pharmacological, and genetic conditions[reference:105]. Elevated T4 may be observed in pregnancy, estrogen therapy, and hereditary TBG elevation[reference:106]. Depressed T4 levels may occur in nephrotic, hepatic, gastrointestinal, and neoplastic disorders[reference:107]. In rat models, accurate total T4 quantification is essential for thyroid function assessment. The Rat Thyroxine (T4) ELISA Kit (KTE100170) delivers precise, reproducible T4 measurement. Sandwich ELISA: Dual-Antibody Capture for Thyroid Hormone Specificity This kit employs…
KTE100169 | Rat Tri-iodothyronine (T3) ELISA Kit — Quantifying the Most Metabolically Active Thyroid Hormone in Rat Models
T3: The Thyroid Hormone That Does the Real Work While T4 is the thyroid‘s primary secretory product, T3 is the hormone that actually gets things done. Although T3 represents only approximately 5% of thyroid hormones in serum, it possesses greater intrinsic metabolic activity, faster turnover, and a larger volume of distribution than circulating T4[reference:88]. T3 binds to nuclear receptors to regulate gene transcription, influencing metabolism, thermogenesis, growth, and development. In rat models, accurate T3 quantification is essential for understanding thyroid function, metabolic regulation, and the effects of endocrine disruptors. The Rat Tri-iodothyronine (T3) ELISA Kit (KTE100169) delivers precise, reproducible T3 measurement. Sandwich ELISA: Dual-Antibody Capture for Thyroid Hormone Specificity This kit employs a two-site sandwich ELISA to quantitate T3 in…
KTE100168 | Rat Testosterone (T) ELISA Kit — Precision Androgen Quantification for Male Reproductive and Metabolic Research
Testosterone: The Primary Male Sex Hormone, Precisely Quantified Testosterone is the primary male sex hormone and an anabolic steroid—the driving force behind male reproductive tissue development (testis and prostate), secondary sexual characteristics (muscle and bone mass, body hair growth), and overall health and well-being[reference:71]. Testosterone insufficiency in males leads to frailty, bone loss, and a cascade of metabolic abnormalities[reference:72]. In rat models—the most widely used preclinical system for reproductive, endocrine, and metabolic research—accurate testosterone quantification is indispensable. The Rat Testosterone (T) ELISA Kit (KTE100168) delivers precise, reproducible testosterone measurement. Sandwich ELISA: Dual-Antibody Capture for Androgen Specificity This kit employs a two-site sandwich ELISA to quantitate testosterone (T) in samples[reference:73]. An antibody specific for T is pre-coated onto a microplate. Standards…
KTE100060 | Rat Cardiac troponin T (cTn-T) ELISA Kit — The Gold Standard Biomarker for Cardiac Injury, Now for Rat Models
cTn-T: The Unmistakable Signature of Myocardial Damage Cardiac troponin T (cTn-T) is a structural protein unique to cardiac muscle cells—and it is the undisputed gold standard biomarker for myocardial injury. When cardiac cells are damaged—whether by ischemia, reperfusion, cardiotoxic drugs, or mechanical stress—cTn-T is rapidly released into the bloodstream. Its cardiac specificity is exceptional: skeletal muscle injury does not cause cross-reactivity. In rat models, cTn-T quantification is the cornerstone of cardiovascular safety assessment, ischemia-reperfusion research, and cardioprotective drug development. The Rat Cardiac troponin T (cTn-T) ELISA Kit (KTE100060) delivers precise, reproducible cTn-T quantification. Sandwich ELISA: Dual-Antibody Capture for Cardiac-Specific Detection This kit employs a two-site sandwich ELISA to quantitate cTn-T in samples[reference:56]. An antibody specific for cTn-T is pre-coated onto…
KTE100034 | Rat Thyroid Stimulating Hormone (TSH) ELISA Kit — The Pituitary‘s Master Switch, Quantified with Precision
TSH: The Conductor of the Thyroid Symphony Thyroid-stimulating hormone (TSH) is the pituitary‘s primary messenger to the thyroid gland—a noncovalently linked glycoprotein heterodimer sharing a common alpha subunit with other pituitary hormones, while its unique beta subunit confers specificity[reference:41]. TSH stimulates thyroid follicular cells to synthesize and secrete thyroid hormones (T4 and T3), making it the master regulator of the hypothalamic-pituitary-thyroid (HPT) axis. In the rat model—the most widely used preclinical system for endocrine research—accurate TSH quantification is essential for understanding thyroid function, evaluating endocrine disruptors, and developing novel thyroid therapeutics. Sandwich ELISA: Dual-Antibody Capture for Maximum Specificity The Rat Thyroid Stimulating Hormone (TSH) ELISA Kit (KTE100034) employs a two-site sandwich ELISA to quantitate TSH in samples[reference:42]. An antibody specific…
KTE0005 | EliKine™ Free Thyroxine (fT4) ELISA Kit — The Gold Standard for Thyroid Function Assessment
fT4: The Thyroid‘s Primary Secretory Product, Measured at Its Bioactive Core Thyroxine (T4) is the principal hormone secreted by the thyroid gland—accounting for approximately 90% of thyroid hormone output. But here is the catch: over 99% of circulating T4 is bound to carrier proteins, primarily thyroxine-binding globulin (TBG)[reference:25]. Only the free, unbound portion (free T4, or fT4) is biologically active[reference:26]. In normal thyroid function, as carrier protein concentrations fluctuate, total T4 levels change to maintain constant free T4[reference:27]. This makes fT4 the most reliable indicator of actual thyroid status—particularly when TBG levels are altered by pregnancy, estrogen therapy, liver disease, or genetic conditions[reference:28]. The EliKine™ Free Thyroxine (fT4) ELISA Kit (KTE0005) delivers precise, reproducible fT4 quantification. Competitive ELISA: Engineered for…
KTE0004 | EliKine™ Free Triiodothyronine (fT3) ELISA Kit — Capturing the Biologically Active Fraction of Thyroid Hormone
fT3: The Active Face of Thyroid Hormone Triiodothyronine (T3) is the most biologically active thyroid hormone—possessing approximately three to five times the metabolic activity of T4. But here is the critical detail: the vast majority of T3 in circulation is bound to carrier proteins. Only the free, unbound fraction (free T3, or fT3) can enter target cells and exert biological effects. Measuring total T3 tells you what is present. Measuring fT3 tells you what is actually working. The EliKine™ Free Triiodothyronine (fT3) ELISA Kit (KTE0004) delivers precisely that—accurate quantification of the biologically active fraction. Competitive ELISA: Designed for Free Hormone Detection KTE0004 employs the competitive inhibition enzyme immunoassay technique. The microtiter plate is pre-coated with an antibody specific to fT3.…
KTE0003 | EliKine™ Estradiol ELISA Kit — Ultrasensitive Estrogen Detection for Reproductive Biology, Oncology, and Beyond
Estradiol: The Most Potent Estrogen, The Most Demanding Assay Estradiol (E2) is the most potent and prevalent estrogen in the human body—a critical regulator of female reproductive development, menstrual cyclicity, bone metabolism, and cardiovascular health. It also plays an undeniable role in hormone-dependent cancers, including breast and endometrial carcinoma. But here is the challenge: estradiol circulates at picomolar concentrations (pmol/L). Detecting these vanishingly low levels demands an assay with exceptional sensitivity and specificity. The EliKine™ Estradiol ELISA Kit (KTE0003) rises to that challenge. Competitive ELISA: Designed for Small Molecule Precision Like its progesterone counterpart, the Estradiol ELISA Kit employs the competitive inhibition enzyme immunoassay technique. The microtiter plate is pre-coated with an antibody specific to estradiol. Standards or samples compete…
KTE0002 | EliKine™ Progesterone ELISA Kit — Precision Steroid Hormone Quantification for Reproductive and Endocrine Research
Progesterone: The Master Regulator of Reproduction and Beyond Progesterone is far more than a "pregnancy hormone." This endogenous steroid and progestogen sex hormone orchestrates the menstrual cycle, sustains pregnancy, guides embryogenesis, and even modulates brain function as a neurosteroid[reference:0]. As a crucial metabolic intermediate in the biosynthesis of other endogenous steroids—including sex hormones and corticosteroids—progesterone sits at the crossroads of multiple endocrine pathways[reference:1]. Whether you are investigating polycystic ovary syndrome (PCOS), evaluating endocrine-disrupting chemicals, or developing novel reproductive therapeutics, accurate progesterone quantification is non-negotiable. Competitive ELISA Technology: Precision Where It Matters Most The EliKine™ Progesterone ELISA Kit (KTE0002) employs the competitive inhibition enzyme immunoassay technique[reference:2]. The microtiter plate is pre-coated with goat-anti-rabbit antibody. Standards or samples are added alongside an…
