Cytokines, what you need and what we have

Cytokines are small proteins (~5–20 kDa) that are crucial in controlling the growth and activity of other immune system cells and blood cells. Cytokines have been shown to be involved in autocrine, paracrine and endocrine signaling as immunomodulating agents. When released, they signal the immune system to do its job.

(Image source: Google)

Cytokine is a general name; other names include chemokines, interferons, interleukins, lymphokines, and tumour necrosis factors, but generally not hormones or growth factors (despite some overlap in the terminology). Cytokines are produced by a broad range of cells, including immune cells like macrophages, B lymphocytes, T lymphocytes and mast cells, as well as endothelial cells, fibroblasts, and various stromal cells; a given cytokine may be produced by more than one type of cell. They act through cell surface receptors and are especially important in the immune system;  It is common for different cell types to secrete the same cytokine or for a single cytokine to act on several different cell types (pleiotropy).

(Image source: Cytokines, Inflammation and Pain)

Cytokines can have either pro- or anti-inflammatory effects, and these effects can be contextual. For inflammation, cytokines can be divided into two categories. One is Pro-inflammatory cytokines, such as IL-1β, IL-6, IL-12, TNF, IFN-γ, etc., which can help activate the tree Dendritic cells, pro-inflammatory macrophages, neutrophils, effector T cells, B cells, etc., promote the occurrence and development of inflammatory reactions; The other type is anti-inflammatory cytokines, such as IL-4, IL-10 , IL-13, TGF-β, etc., can help activate regulatory T cells (Treg), anti-inflammatory macrophages, etc., regulate inflammation, and "neutralize" the effects of pro-inflammatory cytokines.

The cytokines provided by Abbkine include interleukin, chemokine, colony stimulating factor (CSF), interferon, transforming growth factor (TGF) and tumor necrosis factor (TNF), which are used in cancer, apoptosis, endocrinology, immunology, neuroscience, protease and stem cell research. These cytokines have been rigorously verified to meet the demand of R&D personnel for high quality, high biological activity and competitive price. The specific product list is as follows: