EliKine™ Human TIMP-1 ELISA Kit: Precision Quantification of the Master MMP Inhibitor
TIMP-1: The Gatekeeper of Extracellular Matrix Remodeling Tissue inhibitor of metalloproteinases 1 (TIMP-1) is a glycoprotein that functions as a natural inhibitor of matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix[reference:29]. Beyond its inhibitory role, TIMP-1 promotes cell proliferation in a wide range of cell types[reference:30]. TIMP-1 dysregulation is implicated in cancer invasion, fibrosis, arthritis, and cardiovascular disease. EliKine™ Technology for Sensitive TIMP-1 Detection Abbkine's EliKine™ Human TIMP-1 ELISA Kit (KTE6031) employs a two-site sandwich ELISA with proprietary EliKine™ Streptavidin-HRP conjugates[reference:31]. The kit delivers high sensitivity and excellent specificity for Human TIMP-1 with no significant cross-reactivity or interference from analogues[reference:32]. Exceptional Sensitivity: Detect Down to 9.4 pg/mL Parameter Specification Calibration Range 9.4 – 600 pg/mL[reference:33] Limit…
Human TMED9 ELISA Kit: Precision Detection of the Emerging ER-Golgi Trafficking Biomarker
TMED9: The Trafficking Protein with Emerging Clinical Relevance Transmembrane emp24 domain-containing protein 9 (TMED9) is a member of the TMED family of proteins involved in protein trafficking between the endoplasmic reticulum (ER) and the Golgi apparatus. Recent studies have implicated TMED9 dysregulation in cancer progression, neurodegenerative diseases, and cellular stress responses. As an emerging biomarker, accurate TMED9 quantification is increasingly important for cell biology and translational research. Sandwich ELISA Format with Unmatched Specificity Abbkine's Human TMED9 ELISA Kit (KTE60300) employs a two-site sandwich ELISA with a TMED9-specific antibody pre-coated onto the microplate. The kit delivers high sensitivity and excellent specificity for Human TMED9 with no significant cross-reactivity or interference from analogues. Broad Sample Compatibility Sample Type Compatibility Serum ✓ Plasma ✓ Cell…
EliKine™ Human TGF-β1 ELISA Kit: Precision Quantification of the Master Immunoregulatory Cytokine
TGF-β1: The Cytokine That Does It All Transforming Growth Factor Beta 1 (TGF-β1) is a pleiotropic cytokine with profound effects on immune regulation, cell proliferation, differentiation, apoptosis, and extracellular matrix production. It is a key player in fibrosis, cancer progression, wound healing, and autoimmune diseases. Accurate TGF-β1 quantification is essential for immunology, oncology, and fibrosis research. EliKine™ Technology for Reliable TGF-β1 Detection Abbkine's EliKine™ Human TGF-β1 ELISA Kit (KTE6030) employs a two-site sandwich ELISA with proprietary EliKine™ Streptavidin-HRP conjugates. The kit delivers high sensitivity and excellent specificity for Human TGF-β1 with no significant cross-reactivity or interference from analogues. Broad Sample Compatibility Sample Type Compatibility Serum ✓ Plasma ✓ Cell Culture Supernatants ✓ Other Biological Fluids ✓ Complete Kit – Ready to Use…
EliKine™ Human β-NGF ELISA Kit: Precision Neurotrophin Detection for Neuroscience Research
β-NGF: The Neurotrophin That Shapes the Nervous System β-Nerve Growth Factor (β-NGF) is a member of the NGF-beta family that homodimerizes to form the active signaling molecule[reference:20]. It regulates the growth and differentiation of sympathetic and certain sensory neurons[reference:21]. Mutations in the β-NGF gene are associated with hereditary sensory and autonomic neuropathy type 5 (HSAN5), and dysregulated β-NGF expression is implicated in neurodegenerative diseases, chronic pain, and cancer[reference:22]. EliKine™ Technology for Sensitive Neurotrophin Detection Abbkine's EliKine™ Human β-NGF ELISA Kit (KTE6028) employs a two-site sandwich ELISA with proprietary EliKine™ Streptavidin-HRP conjugates[reference:23]. The kit delivers high sensitivity and excellent specificity for Human β-NGF with no significant cross-reactivity or interference from analogues[reference:24]. Exceptional Sensitivity: Detect Down to 16 pg/mL Parameter Specification Calibration Range 31.25…
EliKine™ Human MMP-9 ELISA Kit: Precision Detection of the Extracellular Matrix Remodeling Master Enzyme
MMP-9: The Gelatinase at the Heart of Tissue Remodeling and Disease Matrix metalloproteinase 9 (MMP-9), also known as gelatinase B, is a zinc-dependent endopeptidase that degrades type IV collagen and gelatin—key components of the extracellular matrix (ECM). MMP-9 is involved in tissue remodeling, wound healing, angiogenesis, and immune cell migration. Its dysregulation is implicated in cancer metastasis, atherosclerosis, arthritis, and neurodegenerative diseases. EliKine™ Technology for Accurate MMP-9 Quantification Abbkine's EliKine™ Human MMP-9 ELISA Kit (KTE6027) employs a two-site sandwich ELISA with proprietary EliKine™ Streptavidin-HRP conjugates. The kit delivers high sensitivity and excellent specificity for Human MMP-9 with no significant cross-reactivity or interference from analogues. Broad Sample Compatibility Sample Type Compatibility Serum ✓ Plasma ✓ Cell Culture Supernatants ✓ Other Biological Fluids ✓…
EliKine™ Human Leptin ELISA Kit: Precision Adipokine Quantification for Obesity and Metabolic Research
Leptin: The Satiety Hormone with Far-Reaching Metabolic Implications Leptin, the 16-kDa adipokine encoded by the ob gene, is the primary signal from adipose tissue communicating energy status to the hypothalamus. Beyond appetite regulation, leptin influences reproduction, immune function, bone metabolism, and insulin sensitivity. Leptin dysregulation is central to obesity, type 2 diabetes, and metabolic syndrome. EliKine™ Technology for Reliable Leptin Detection Abbkine's EliKine™ Human Leptin ELISA Kit (KTE6026) employs a two-site sandwich ELISA format with proprietary EliKine™ Streptavidin-HRP conjugates. The kit delivers high sensitivity and excellent specificity for Human Leptin with no significant cross-reactivity or interference from analogues. Broad Sample Compatibility Sample Type Compatibility Serum ✓ Plasma ✓ Cell Culture Supernatants ✓ Other Biological Fluids ✓ Complete Kit – Ready to Use…
EliKine™ Human IL-23 ELISA Kit: Accurate Quantification of the Th17 Polarization Master Switch
IL-23: The Cytokine Driving Autoimmunity and Chronic Inflammation Interleukin-23 (IL-23) is a heterodimeric cytokine composed of p19 and p40 subunits. It is a master regulator of Th17 cell differentiation and maintenance, driving the production of IL-17A, IL-17F, and other pro-inflammatory cytokines. IL-23 is centrally implicated in psoriasis, inflammatory bowel disease, multiple sclerosis, and rheumatoid arthritis—making it a prime therapeutic target. EliKine™ Technology for Superior Sensitivity Abbkine's EliKine™ Human IL-23 ELISA Kit (KTE6025) employs a two-site sandwich ELISA with proprietary EliKine™ Streptavidin-HRP conjugates for enhanced signal detection. The kit delivers high sensitivity and excellent specificity for Human IL-23 with no significant cross-reactivity or interference from analogues. Broad Sample Compatibility Sample Type Compatibility Serum ✓ Plasma ✓ Cell Culture Supernatants ✓ Other Biological Fluids…
EliKine™ Human IL-22 ELISA Kit: Precision Cytokine Detection for Inflammation and Barrier Immunity Research
IL-22: The Dual-Function Cytokine at the Heart of Inflammation Interleukin-22 (IL-22) is a member of the IL-10 family of cytokines, produced by NK cells and Th1-type T cells[reference:11]. It plays a dual role in inflammation—promoting tissue repair and antimicrobial defense at barrier surfaces while also driving pathological inflammation in autoimmune diseases like psoriasis and inflammatory bowel disease[reference:12]. Accurate IL-22 quantification is essential for understanding these opposing functions. EliKine™ Technology: Proprietary Streptavidin-HRP for Superior Signal Abbkine's EliKine™ Human IL-22 ELISA Kit (KTE6024) leverages proprietary EliKine™ Streptavidin-HRP conjugates for enhanced signal-to-noise ratio[reference:13]. The two-site sandwich ELISA format ensures specific capture and detection of IL-22[reference:14]. Exceptional Sensitivity: Detect Down to 8 pg/mL Parameter Specification Calibration Range 15.63 – 1000 pg/mL[reference:15] Limit of Detection 8 pg/mL[reference:16]…
Human TNFAIP8L2 ELISA Kit: Unlocking the Immune Regulation Puzzle with Precision
TNFAIP8L2: The Immune Checkpoint You Need to Measure Tumor necrosis factor alpha-induced protein 8-like protein 2 (TNFAIP8L2), also known as TIPE2, is a critical negative regulator of inflammation and immune homeostasis[reference:5]. It maintains T-cell receptor signaling and prevents autoimmune pathology. Dysregulated TNFAIP8L2 expression has been linked to inflammatory diseases, autoimmune disorders, and cancer immune evasion. Quantifying TNFAIP8L2 accurately in patient samples has been challenging—until now. Sandwich ELISA Format with Unmatched Specificity Abbkine's Human TNFAIP8L2 ELISA Kit (KTE60230) employs a two-site sandwich ELISA with a TNFAIP8L2-specific antibody pre-coated onto the microplate[reference:6]. After capturing the target, a biotin-conjugated detection antibody and Streptavidin-HRP generate a colorimetric signal proportional to TNFAIP8L2 concentration[reference:7]. No Cross-Reactivity, No Compromise The kit demonstrates no significant cross-reactivity or interference between Human TNFAIP8L2 and…
Human OPG ELISA Kit: Precision Quantification of the Master Osteoclast Regulator
OPG: The Bone Metabolism Biomarker You Can't Afford to Misquantify Osteoprotegerin (OPG) is a secreted cytokine that functions as a decoy receptor for RANKL, blocking osteoclast differentiation and bone resorption[reference:0]. Its dysregulation is implicated in osteoporosis, rheumatoid arthritis, cancer metastasis, and cardiovascular calcification. Accurate OPG quantification is therefore indispensable for bone biology, oncology, and metabolic research. Yet many commercial OPG ELISA kits suffer from cross-reactivity with TNFRSF11B homologs, narrow dynamic ranges, and inconsistent lot-to-lot performance. Superior Specificity: No Cross-Reactivity, No False Signals Abbkine's Human OPG ELISA Kit (KTE60224) employs a two-site sandwich ELISA format with a monoclonal antibody specific for TNFRSF11B pre-coated onto the microplate[reference:1]. The kit demonstrates no significant cross-reactivity or interference between Human TNFRSF11B and its analogues[reference:2]—a critical advantage over generic kits…
