EliKine™ Human TIMP-1 ELISA Kit: Precision Quantification of the Master MMP Inhibitor
TIMP-1: The Gatekeeper of Extracellular Matrix Remodeling
Tissue inhibitor of metalloproteinases 1 (TIMP-1) is a glycoprotein that functions as a natural inhibitor of matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix[reference:29]. Beyond its inhibitory role, TIMP-1 promotes cell proliferation in a wide range of cell types[reference:30]. TIMP-1 dysregulation is implicated in cancer invasion, fibrosis, arthritis, and cardiovascular disease.
EliKine™ Technology for Sensitive TIMP-1 Detection
Abbkine's EliKine™ Human TIMP-1 ELISA Kit (KTE6031) employs a two-site sandwich ELISA with proprietary EliKine™ Streptavidin-HRP conjugates[reference:31]. The kit delivers high sensitivity and excellent specificity for Human TIMP-1 with no significant cross-reactivity or interference from analogues[reference:32].
Exceptional Sensitivity: Detect Down to 9.4 pg/mL
| Parameter | Specification |
|---|---|
| Calibration Range | 9.4 – 600 pg/mL[reference:33] |
| Limit of Detection | 9.4 pg/mL[reference:34] |
| Sample Types | Serum, plasma, cell culture supernatants[reference:35] |
Complete Kit Components
Includes TIMP-1 microplate, standard, detection antibody, EliKine™ Streptavidin-HRP, standard diluent, assay buffer, HRP substrate, stop solution, wash buffer, and plate covers[reference:36].
Why Choose KTE6031?
| Feature | KTE6031 | Generic Competitors |
|---|---|---|
| Detection Range | 9.4–600 pg/mL | Variable |
| LOD | 9.4 pg/mL | Often higher |
| Streptavidin-HRP | Proprietary EliKine™ | Generic |
| Specificity | No cross-reactivity | Variable |
The Bottom Line
Whether you're studying cancer metastasis, fibrosis, or inflammatory tissue damage, KTE6031 delivers the sensitivity and specificity your research demands.
📎 Reference: EliKine™ Human TIMP-1 ELISA Kit (KTE6031)
