KTE101106 | Rat Glutamate (Glu) ELISA Kit — The Excitatory Neurotransmitter, Quantified with Precision
Glutamate: The Brain's Primary Excitatory Neurotransmitter Glutamate is the most abundant excitatory neurotransmitter in the mammalian central nervous system—responsible for the vast majority of fast excitatory synaptic transmission. Beyond its role in neurotransmission, glutamate is a key metabolite in the glutamate-glutamine cycle, linking neurotransmitter pools to energy metabolism and ammonia detoxification. Dysregulated glutamate signaling is implicated in excitotoxicity, ischemia, traumatic brain injury, and neurodegenerative diseases. In rat models, glutamate quantification is essential for neuroscience research. Competitive ELISA: Designed for Small-Molecule Neurotransmitter Detection As a small-molecule amino acid, glutamate requires a competitive assay format for accurate quantification. KTE101106 employs the competitive enzyme immunoassay technique, where sample glutamate competes with HRP-conjugated glutamate for binding to a pre-coated antibody. The intensity of color…
KTE101023 | Rat Super Oxidase Dimutase (SOD) ELISA Kit — Quantify the Enzyme That Defends Against Superoxide Radicals
SOD: The First Line of Enzymatic Antioxidant Defense Superoxide dismutase (SOD) is the enzyme that catalyzes the dismutation of the superoxide radical (O₂⁻) to hydrogen peroxide and molecular oxygen—one of the most critical antioxidant reactions in biology. SOD exists in three forms: cytosolic Cu/Zn-SOD (SOD1), mitochondrial Mn-SOD (SOD2), and extracellular SOD (SOD3). Together, they protect cells from the damaging effects of superoxide, a byproduct of mitochondrial respiration and a key driver of oxidative stress. In rat models, SOD activity or concentration is a core readout for oxidative stress status and antioxidant capacity. Sandwich ELISA: Direct Quantification of a Key Antioxidant Enzyme KTE101023 employs a sandwich ELISA format to quantitate SOD in samples. An antibody specific for SOD is pre-coated onto…
KTE101019 | Rat Cardiac troponin I (cTn-I) ELISA Kit — The Most Specific Biomarker for Cardiac Injury, Now for Rat Models
cTn-I: The Unmistakable Signature of Myocardial Damage Cardiac troponin I (cTn-I) is one of three subunits of the troponin complex in cardiac muscle—alongside troponin T (TnT) and troponin C (TnC)[reference:35]. As the inhibitory subunit, TnI prevents actin-myosin interaction in the absence of calcium. But more importantly, cTn-I is exclusively expressed in cardiac muscle—making it the most specific biomarker for myocardial injury. When cardiac cells are damaged, cTn-I is rapidly released into the bloodstream, and its elevation is the gold standard for diagnosing acute myocardial infarction. In rat models, cTn-I quantification is essential for cardiovascular safety assessment and cardioprotective drug development. Sandwich ELISA: Cardiac-Specific Detection with Dual-Antibody Capture KTE101019 employs a two-site sandwich ELISA to quantitate cTn-I in samples. An antibody…
KTE100947 | Rat Estradiol antibody (E2-Ab) ELISA Kit — Quantify the Autoantibody That Reflects Estrogen Status
E2-Ab: The Autoantibody That Tracks Estrogen Exposure Estradiol (E2) is the most potent endogenous estrogen, essential for female reproductive function and present at lower levels in males. But estradiol is not only a hormone—it can also act as a hapten, triggering the production of anti-estradiol antibodies (E2-Ab). Quantifying E2-Ab levels provides insight into estrogen exposure, endocrine disruption, and possibly autoimmune responses. In rat models, E2-Ab measurement is valuable for reproductive toxicology, endocrine research, and immunology studies. Competitive ELISA: Designed for Small-Molecule Antibody Detection KTE100947 employs the competitive enzyme immunoassay technique. The microtiter plate is pre-coated with an antibody specific to E2-Ab. Standards or samples are added alongside HRP-conjugated E2-Ab, and a competitive inhibition reaction occurs between HRP-labeled and unlabeled E2-Ab…
KTE100847 | Rat Catalase (CAT) ELISA Kit — Quantify the Enzyme That Breaks Down Hydrogen Peroxide
Catalase: The Cell's Hydrogen Peroxide Scavenger Catalase (CAT) is a heme-containing enzyme that catalyzes the decomposition of hydrogen peroxide (H₂O₂) to water and oxygen—one of the most efficient enzymatic reactions in biology, with a turnover rate of millions of molecules per second. Alongside superoxide dismutase (SOD) and glutathione peroxidase (GPx), catalase forms the front line of enzymatic antioxidant defense. In rat models, catalase activity or concentration is a key indicator of oxidative stress status and antioxidant capacity. Sandwich ELISA: Direct Quantification of a Key Antioxidant Enzyme KTE100847 employs a sandwich ELISA format to quantitate catalase in samples. An antibody specific for catalase is pre-coated onto a microplate. Standards and samples are added, and any catalase present is captured by the…
KTE100838 | Rat Glutathione (GSH) ELISA Kit — The Master Antioxidant, Quantified with Precision
GSH: The Cell's First Line of Defense Against Oxidative Stress Glutathione (GSH) is the most abundant intracellular thiol and the primary antioxidant defense system in mammalian cells. This tripeptide (γ-glutamyl-cysteinyl-glycine) directly neutralizes reactive oxygen species, regenerates other antioxidants (vitamins C and E), and maintains the redox balance essential for cellular function. GSH depletion is a hallmark of oxidative stress and is implicated in aging, neurodegeneration, liver disease, and cancer. In rat models, GSH quantification is a critical readout for oxidative stress assessment. Competitive ELISA: Accurate Quantification of a Small-Molecule Antioxidant As a small molecule, GSH requires a competitive assay format for accurate quantification. KTE100838 employs the competitive enzyme immunoassay technique, where sample GSH competes with HRP-conjugated GSH for binding to…
KTE100827 | Rat Nuclear factor-kappa B (NF-kB) ELISA Kit — Quantify the Master Transcription Factor of Inflammation and Immunity
NF-kB: The Conductor of the Inflammatory Symphony Nuclear factor-kappa B (NF-kB) is arguably the most important transcription factor in immunology—a family of proteins that controls the expression of genes involved in inflammation, immunity, cell proliferation, and survival. NF-kB activation is triggered by cytokines (TNF-α, IL-1), pathogens, and stress signals, making it a central player in everything from infectious disease to cancer. In rat models, NF-kB quantification is essential for studying inflammatory disease, drug response, and immune regulation. Sandwich ELISA: Direct Quantification of a Nuclear Transcription Factor KTE100827 employs a two-site sandwich ELISA to quantitate NFKB1 (p50) in samples. An antibody specific for NFKB1 is pre-coated onto a microplate. Standards and samples are added, and any NFKB1 present is captured by…
KTE100733 | Rat Follicle-stimulating hormone (FSH) ELISA Kit — The Essential Partner for Reproductive Axis Studies in Rat Models
FSH: The Hormone That Starts It All Follicle-stimulating hormone (FSH) is one of the two key gonadotropins produced by the anterior pituitary—the essential partner to LH in regulating reproduction. In females, FSH stimulates ovarian follicle growth and maturation; in males, it drives spermatogenesis in the Sertoli cells of the testes. FSH levels are tightly regulated by gonadal feedback, making it a critical readout for studying the HPG axis, infertility, and endocrine disruption. Sandwich ELISA: Specific, Sensitive, and Reproducible KTE100733 employs a two-site sandwich ELISA to quantitate FSH in samples. An antibody specific for FSH is pre-coated onto a microplate. Standards and samples are added, and any FSH present is captured by the immobilized antibody. After washing, an HRP-conjugated detection antibody…
KTE100699 | Rat Luteotropic hormone (LH) ELISA Kit — Precision Pituitary Hormone Quantification for Reproductive and Endocrine Research
LH: The Trigger That Controls Ovulation and Steroidogenesis Luteotropic hormone (LH)—also known as luteinizing hormone—is a glycoprotein hormone produced by the anterior pituitary gland. Alongside FSH, LH regulates the reproductive system: in females, the mid-cycle LH surge triggers ovulation and promotes corpus luteum formation; in males, LH stimulates Leydig cells to produce testosterone. In rat models, LH quantification is essential for studying the hypothalamic-pituitary-gonadal (HPG) axis, reproductive toxicology, and endocrine disorders. Sandwich ELISA: Dual-Antibody Capture for Hormonal Specificity KTE100699 employs a two-site sandwich ELISA to quantitate LH in samples. An antibody specific for LH is pre-coated onto a microplate. Standards and samples are added, and any LH present is captured by the immobilized antibody. After washing, an HRP-conjugated detection antibody…
KTE100650 | Rat Malondialdehyde (MDA) ELISA Kit — The Gold Standard for Lipid Peroxidation Quantification in Rat Models
MDA: The Definitive Marker of Oxidative Stress Lipid peroxidation is one of the most damaging consequences of oxidative stress, and malondialdehyde (MDA) is its most widely measured end-product. When reactive oxygen species (ROS) attack polyunsaturated fatty acids in cellular membranes, a cascade of degradation reactions produces MDA—a highly reactive dialdehyde that cross-links proteins, DNA, and other biomolecules. In rat models of cardiovascular disease, neurodegeneration, liver injury, and diabetes, MDA is the biomarker that tells you whether oxidative damage is actually occurring. Competitive ELISA: Precision Quantification of a Small-Molecule Marker Unlike protein-based biomarkers, MDA is a small molecule that requires a competitive assay format for accurate quantification. KTE100650 employs the competitive enzyme immunoassay technique, where sample MDA competes with HRP-conjugated MDA…
