EliKine™ Human IL-17 ELISA Kit — Application Scenarios for Inflammation and Autoimmune Research
IL-17: A Key Driver of Inflammation and Autoimmunity Interleukin 17 (IL-17) , also known as IL-17A or CTLA8, is a proinflammatory cytokine produced by activated T cells, particularly Th17 cells[reference:130]. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases[reference:131]. IL-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) [reference:132]. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and inflammatory bowel disease[reference:133]. Abbkine's EliKine™ Human IL-17 ELISA Kit (KTE6022) provides researchers with a sensitive, specific, and reliable tool for quantifying this critical proinflammatory cytokine in human samples. With 3 publications citing this kit[reference:134], it's a trusted tool in the research community. Here's how researchers across different fields are putting it to work. Autoimmune Disease Research: Th17-Mediated Pathology IL-17 is the signature cytokine of Th17…
EliKine™ Human IL-10 ELISA Kit — Application Scenarios for Immunology and Inflammation Research
IL-10: The Master Anti-Inflammatory Cytokine Interleukin 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes[reference:119]. This cytokine has pleiotropic effects in immunoregulation and inflammation[reference:120]. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages[reference:121]. It also enhances B cell survival, proliferation, and antibody production[reference:122]. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway[reference:123]. Abbkine's EliKine™ Human IL-10 ELISA Kit (KTE6019) provides researchers with a sensitive, specific, and reliable tool for quantifying this essential anti-inflammatory cytokine in human samples. With 3 publications citing this kit[reference:124], it's a trusted tool in the research community. Here's how researchers across different fields are putting it to work. Immunology: Immune Suppression and Tolerance IL-10 is the master anti-inflammatory cytokine that maintains…
EliKine™ Human IL-8 ELISA Kit — Application Scenarios for Inflammation and Cancer Research
IL-8: A Master Regulator of Inflammation and Angiogenesis Interleukin 8 (IL-8) , also known as CXCL8, is a member of the CXC chemokine family[reference:107]. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types[reference:108]. It functions as a chemoattractant for neutrophils and other immune cells, and is also a potent angiogenic factor[reference:109]. IL-8 plays a role in the pathogenesis of bronchiolitis and other inflammatory diseases[reference:110]. Abbkine's EliKine™ Human IL-8 ELISA Kit (KTE6018) provides researchers with a sensitive, specific, and reliable tool for quantifying this critical chemokine in human samples. With 2 publications citing this kit[reference:111], it's a trusted tool in the research community. Here's how researchers across different fields are putting it to work. Inflammation Research: Acute and Chronic Inflammation IL-8 is a key…
EliKine™ Human IL-6 ELISA Kit — Comprehensive Review & Buying Guide
EliKine™ Human IL-6 ELISA Kit: A Critical Review for Inflammation and Immunology Researchers Interleukin 6 (IL-6) is a cytokine that functions in inflammation and the maturation of B cells[reference:91]. The encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections[reference:92]. IL-6 is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor[reference:93]. It is a key biomarker for inflammation, autoimmune diseases, cancer, and COVID-19 (cytokine storm). The EliKine™ Human IL-6 ELISA Kit (KTE6017) from Abbkine provides a sensitive, specific, and complete solution for quantifying IL-6 in human samples. With an impressive 13 publications citing this kit, it's one of the most trusted IL-6 detection tools on the market[reference:94].…
EliKine™ Human IL-1β ELISA Kit — Comprehensive Review & Buying Guide
EliKine™ Human IL-1β ELISA Kit: A Critical Review for Inflammation Researchers Interleukin 1β (IL-1β) is a member of the interleukin 1 cytokine family[reference:76]. Produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE), IL-1β is an important mediator of the inflammatory response and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis[reference:77]. It is a key biomarker for inflammation, autoimmune diseases, infectious diseases, and cancer. The EliKine™ Human IL-1β ELISA Kit (KTE6013) from Abbkine provides a sensitive, specific, and complete solution for quantifying IL-1β in human samples. With 5 publications citing this kit, it's a trusted tool in the research community[reference:78]. Here's what you need to know before buying. What's in the Box? Component Included Human IL-1β microplate…
Human Tubulin beta-4 chain (TUBB4) ELISA Kit — FAQ for Cytoskeleton and Neurobiology Researchers
Human TUBB4 ELISA Kit: Your Questions Answered Tubulin beta-4 chain (TUBB4) , also known as TUBB5 or beta-5 tubulin, is a member of the tubulin family that forms the building blocks of microtubules[reference:55]. Microtubules are essential components of the cytoskeleton, playing critical roles in cell division, intracellular transport, cell motility, and neuronal development. Mutations in TUBB4 are associated with neurological disorders, including hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) . Abbkine's Human Tubulin beta-4 chain (TUBB4) ELISA Kit (KTE60116) provides researchers with a reliable tool for quantifying this important cytoskeletal protein in human samples. Here are answers to the most common questions about this kit. What is the detection principle of this TUBB4 ELISA kit? This kit employs a two-site sandwich ELISA to quantitate TUBB4 in samples[reference:56]. An antibody specific for TUBB4 has…
EliKine™ Human IFN-γ ELISA Kit — Application Scenarios for Immunology and Infectious Disease Research
IFN-γ: A Master Regulator of Immune Responses Interferon-gamma (IFN-γ) is a critical cytokine produced primarily by activated T cells and natural killer (NK) cells. It plays a central role in antiviral defense, immune regulation, macrophage activation, and Th1-mediated immune responses. IFN-γ is a key biomarker for infectious disease, autoimmune disorders, cancer immunotherapy, and vaccine development. Abbkine's EliKine™ Human IFN-γ ELISA Kit (KTE6011) provides researchers with a sensitive, specific, and reliable tool for quantifying this essential cytokine in human samples. Here's how researchers across different fields are putting it to work. Immunology: Th1/Th2 Balance and Immune Polarization IFN-γ is the signature cytokine of Th1 immune responses. Immunologists use this kit to: Quantify IFN-γ secretion in T cell activation assays Monitor Th1/Th2 balance in immune response studies Assess the effects of immunomodulatory compounds on IFN-γ production Study the role…
EliKine™ Human HGF ELISA Kit — Comprehensive Review & Buying Guide
EliKine™ Human HGF ELISA Kit: Is It Right for Your Lab? Hepatocyte Growth Factor (HGF) is a multifunctional cytokine secreted by mesenchymal cells that acts on cells of mainly epithelial origin[reference:40]. HGF binds to the hepatocyte growth factor receptor (c-Met) to regulate cell growth, cell motility, and morphogenesis in numerous cell and tissue types[reference:41]. This protein also plays a critical role in angiogenesis, tumorogenesis, and tissue regeneration[reference:42]. Accurate HGF quantification is essential for researchers studying cancer biology, liver regeneration, wound healing, and developmental biology. The EliKine™ Human HGF ELISA Kit (KTE6009) from Abbkine offers a sensitive, specific, and complete solution for quantifying HGF in human samples. Here's our detailed review. What's in the Box? Component Included Human HGF microplate ✅ Human HGF standard ✅ Human HGF detect antibody ✅ EliKine™…
Human Cytochrome b-c1 Complex Subunit 10 (UQCR) ELISA Kit — FAQ for Mitochondrial and Energy Metabolism Researchers
Human UQCR ELISA Kit: Your Questions Answered UQCR (Ubiquinol-Cytochrome c Reductase Complex Subunit 10) , also known as QCR10, is a critical component of the mitochondrial respiratory chain. It is a subunit of the cytochrome b-c1 complex (Complex III), which plays an essential role in electron transport and ATP production during oxidative phosphorylation. Dysregulation of mitochondrial complex subunits is implicated in mitochondrial diseases, neurodegenerative disorders, and metabolic syndromes[reference:20]. Abbkine's Human Cytochrome b-c1 complex subunit 10 (UQCR) ELISA Kit (KTE60084) provides researchers with a reliable tool for quantifying this important mitochondrial protein in human samples. Here are answers to the most common questions about this kit. What is the detection principle of this UQCR ELISA kit? This kit employs a two-site sandwich ELISA to quantitate UQCR in samples[reference:21]. An antibody specific for UQCR has been pre-coated…
Human Vitamin A (VA) ELISA Kit — FAQ for Nutrition and Metabolism Researchers
Human Vitamin A (VA) ELISA Kit: Your Questions Answered Vitamin A is a group of unsaturated nutritional organic compounds that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids (most notably beta-carotene). Vitamin A has multiple functions: it is important for growth and development, for the maintenance of the immune system and good vision. Vitamin A is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision.[reference:0] Abbkine's Human Vitamin A (VA) ELISA Kit (KTE60075) provides researchers with a reliable tool for quantifying this essential vitamin in human samples. Here are answers to the most common questions about this kit and vitamin A detection.…
