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Wuhan Institute of Virology Reveals New Coronavirus (2019-nCoV) may Bat Origin

On February 3, the Wuhan virus research institute of the Chinese academy of sciences/biosafety research center, Wuhan jinyintan hospital and Hubei provincial center for disease prevention and control cooperated in the identification and research of 2019 new coronavirus (2019-nCoV), which caused the Wuhan pneumonia epidemic, and published it online under the topic "a pneumonia outbreak associated with a new coronavirus of disease origin" (the link of the paper is https://www.nature.com/articles/s41586-020-2012-7). Relevant research teams revealed the basic biological characteristics of the coronavirus from nucleic acid detection, serological diagnosis, virus isolation and receptor utilization, providing important clues for epidemic control and drug research and development. The research team obtained the whole genome sequence of the virus from the early samples of 5…

2020-02-06 2280 views

Protein Quantification- Reliable and Stable Choice of Excellence

Accurate protein quantification is necessary for protein-related experiments that involve research in molecular biology, cell biology, biochemistry, developmental biology, and neuroscience. Abbkine protein quantification products include Protein Quantification Kits (BCA Assay and Bradford Assay), SuperLumia ECL HRP Substrate Kit, Protein Gel Flash Staining Kit, Colorcode Prestained Protein Marker and so on. Protein Quantification Kits Featured products: 1. Protein Quantification Kits (BCA Assay) • Save time—Easier and 4x faster than traditional Lowry methods. • High sensitivity—The detection line is as low as 25ug/ml, and the minimum detection protein is 0.5ug. • Good compatibility—unaffected by most ionic and non-ionic detergents. Compatible with up to 5% SDS, 5% Triton X-100, 5% Tween-20, 60, 80 in the sample. • Excellent linearity-linear standard curve range:…

2020-01-16 1765 views

Hard work, Do not forget your initiative mind-—Abbkine Breaks 1400 citations

Since Abbkine document collection began, as of December 31, 2019, the number of English articles published by google using Abbkine products has exceeded 1400, with an impact factor exceeding 5400 points. Thank you for your trust and support to Abbkine. We will continuously stimulate our internal creativity, provide competitive biomedical products and services, and continuously create maximum value for our customers. With a view to becoming a respected and world-class provider of biomedical products and services. Figure 1: Number of English Articles Published Using Abbkine Products from 2017 to 2019 In December 2019, Abbkine added 200+ citations. Some high-score citations are as below. 1.LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis. https://doi.org/10.1016/j.cell.2019.07.021 Magazine: Cell Impact: 24.38…

2020-01-09 1468 views

The third generation of fluorescent dye AbFluor™/highly water-soluble fluorescent dye

AbFluor™ dyes are a series of highly water-soluble fluorescent dyes introduced by Abbkine after many years of research, covering the ultraviolet, visible and near-infrared spectrum, suitable for labeling biological macromolecules, especially proteins and nucleic acids. Their excellent hydrophilicity enables protein-conjugated labeling to be performed easily in aqueous media, while minimizing the need for organic solvents. AbFluor™ dyes not only have better fluorescence performance than other fluorescent dyes (such as FITC, TRITC, Alexa Fluor and Dylight dyes), but also the coupling products are more stable. Why recommend AbFluor™ fluorescent dyes? With innovative modifications to the core structure of the dye, AbFluor™ dyes have more brilliant properties than other commercial dyes, including stronger fluorescent brightness, better light stability, wider pH tolerance range,…

2020-01-03 2606 views

Western Blot Product Portfolio- Sample Preparation

Overview of western blot (WB): Western Blot is an experimental method commonly used in molecular biology, biochemistry and immunogenetics. The basic principle is to color the cell or biological tissue samples treated by gel electrophoresis through specific antibodies. Information on the expression of specific proteins in the analyzed cells or tissues is obtained by analyzing the staining position and staining depth. Sample preparation: Good protein is half the success of WB. We need to lyse cells and tissues to extract the target protein. Once cracking occurs, hydrolysis, dephosphorylation and denaturation begin. If appropriate protease or phosphatase inhibitor is added to the cracking solution, these reactions will be greatly slowed down and the chance of extracting good protein will be increased.…

2019-12-25 2295 views

Abbkine Holiday Arrangement of 2020 Spring Festival

Dear partners: Thank you all for giving our company full support in 2019. With the approaching of 2020 Spring Festival, here Abbkine makes the following holiday arrangement: Holiday Time: 20th Jan. 2020-31th Jan. 2020 (12 Days). Holiday Time for the logistics department: 18th Jan. 2020-2nd Feb. 2020 (16 Days). Sorry for the inconvenience caused by the holiday. My sincere regards. Abbkine Scientific Inc 23th Dec.2019

2019-12-23 1472 views

Selected primary antibody| GSK3β Mouse Monoclonal antibody recommendation

Review of Related Articles: Research Hotspots of Cell Apoptosis: Bcl-2 Monoclonal Antibody Abbkine P53 antibody helps basic cancer research! Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody Selected primary antibody|TNF-α antibody recommendation Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase that has been evolutionarily very conservative.The protein encoded by GSK3β (glycogen synthase kinase 3 beta) is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. GSK-3β can also act on many signaling protein structural proteins and transcription factors, and regulate cell differentiation, proliferation, survival and apoptosis. GSK-3β is a key enzyme involved in liver glucose metabolism. It inhibits its activity by phosphorylating GS, reduces liver glucose synthesis, increases…

2019-12-19 1879 views

Selected primary antibody| Cleaved Caspase-3 antibody recommendation

Review of Related Articles: Research Hotspots of Cell Apoptosis: Bcl-2 Monoclonal Antibody Abbkine P53 antibody helps basic cancer research! Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody Selected primary antibody|TNF-α antibody recommendation Cleaved Caspase-3 is an Activated Form of Caspase-3. Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Gene…

2019-12-12 2112 views

Selected primary antibody|TNF-α antibody recommendation

Review of Related Articles: Research Hotspots of Cell Apoptosis: Bcl-2 Monoclonal Antibody Abbkine P53 antibody helps basic cancer research! Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody Tumor necrosis factor (TNF, cachexin, or cachectin; once named as tumor necrosis factor alpha or TNFα) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF is a member of the TNF superfamily, consisting of various transmembrane proteins with a homologous TNF domain. The primary role of TNF is in the regulation…

2019-11-27 2621 views

Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody

ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. In humans, ACTA2 is encoded by the ACTA2 gene located on 10q22-q24. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, Moyamoya disease, and multisystemic smooth muscle dysfunction syndrome. ACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA)…

2019-11-14 2916 views