Abbkine Holiday Arrangement of 2020 Spring Festival
Dear partners: Thank you all for giving our company full support in 2019. With the approaching of 2020 Spring Festival, here Abbkine makes the following holiday arrangement: Holiday Time: 20th Jan. 2020-31th Jan. 2020 (12 Days). Holiday Time for the logistics department: 18th Jan. 2020-2nd Feb. 2020 (16 Days). Sorry for the inconvenience caused by the holiday. My sincere regards. Abbkine Scientific Inc 23th Dec.2019
Selected primary antibody| GSK3β Mouse Monoclonal antibody recommendation
Review of Related Articles: Research Hotspots of Cell Apoptosis: Bcl-2 Monoclonal Antibody Abbkine P53 antibody helps basic cancer research! Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody Selected primary antibody|TNF-α antibody recommendation Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase that has been evolutionarily very conservative.The protein encoded by GSK3β (glycogen synthase kinase 3 beta) is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. GSK-3β can also act on many signaling protein structural proteins and transcription factors, and regulate cell differentiation, proliferation, survival and apoptosis. GSK-3β is a key enzyme involved in liver glucose metabolism. It inhibits its activity by phosphorylating GS, reduces liver glucose synthesis, increases…
Selected primary antibody| Cleaved Caspase-3 antibody recommendation
Review of Related Articles: Research Hotspots of Cell Apoptosis: Bcl-2 Monoclonal Antibody Abbkine P53 antibody helps basic cancer research! Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody Selected primary antibody|TNF-α antibody recommendation Cleaved Caspase-3 is an Activated Form of Caspase-3. Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Gene…
Selected primary antibody|TNF-α antibody recommendation
Review of Related Articles: Research Hotspots of Cell Apoptosis: Bcl-2 Monoclonal Antibody Abbkine P53 antibody helps basic cancer research! Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody Tumor necrosis factor (TNF, cachexin, or cachectin; once named as tumor necrosis factor alpha or TNFα) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF is a member of the TNF superfamily, consisting of various transmembrane proteins with a homologous TNF domain. The primary role of TNF is in the regulation…
Marker of myofibroblast antibody-α-SMA/ACTA2 Monoclonal Antibody
ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. In humans, ACTA2 is encoded by the ACTA2 gene located on 10q22-q24. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, Moyamoya disease, and multisystemic smooth muscle dysfunction syndrome. ACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA)…
Abbkine winter promotion: looking for you who need live-cell probe
Promotion time: From now to 15th January, 2020. Promotion product list: TraKine™ Pro product line (Tubulin, Lysosome, Mitochondrion, Nuclei live-cell probe ). Details of activities: 20% off for TraKine™ Pro product line. Details for promotion product: Product name #Cat Target Ex/Em (nm) Size Promotion price ($) TraKine™ Pro Live-cell Tubulin Staining kit (Green Fluorescence with Super Resolution) KTC4100 Tubulin 500/520 50/250T 144/496 TraKine™ Pro Live-cell Lysosome Staining kit (Deep Red Fluorescence with Super Resolution) KTC4210 Lysosome 650/665 50/250T 128/472 TraKine™ Pro Live-cell Lysosome Staining kit (Orange Fluorescence with Super Resolution) KTC4220 Lysosome 565/590 50/250T 128/4721 TraKine™ Pro Live-cell Mitochondrion Staining kit (Deep Red Fluorescence with Super Resolution) KTC4300 Mitochondrion 647/661 50/250T 176/576 TraKine™ Pro Live-cell Nuclei Staining kit (Deep Red…
Abbkine P53 antibody helps basic cancer research!
P53 gene, human tumor suppressor gene. The gene encodes a protein with a molecular weight of 43.7KDa, but is named P53 because the protein band appears at 53KDa shown by Marker. Wild-type p53 causes cancer cells to apoptosis, thus preventing canceration; But also has the function of helping cell genes repair defects; Studies have found that mutant p53 can enhance canceration. 50% of human tumors are related to P53 gene. Currently, there are liver cancer, breast cancer, bladder cancer, gastric cancer, colon cancer, prostate cancer, soft tissue sarcoma, ovarian cancer, brain tumor, lymphocyte tumor, esophageal cancer, lung cancer, osteosarcoma, etc. P53 mutation in human tumors is mainly in highly conserved regions, with the highest mutation at 175, 248, 249, 273,…
IL-6: Target Molecule for Cytokine Storms
Interleukin-6 (IL-6) is a multi-effect cytokine that plays an important role in host defense by regulating immune and inflammatory reactions. IL-6 is mainly produced by macrophages, T lymphocytes and B lymphocytes. When the body has inflammatory reaction or infection, various cytokines such as virus, endotoxin and tumor necrosis factor can induce the body to produce IL-6. The biological effects of IL-6 are mainly reflected in inducing B cell differentiation to produce immunoglobulin, promoting T cell proliferation and growth, enhancing blood cell differentiation and its anti-tumor effect, promoting bone marrow hematopoietic stem cell proliferation, etc. IL-6 is an important member of cytokine network and plays a central role in acute inflammatory reaction. The production of IL-6 induces the production of C-reactive…
Abbkine Meets You at 17th International Immunology Congress (IUIS 2019)
Abbkine invites you to visit IUIS 2019, Beijing, China. Abbkine featured products and services will be displayed at the exhibition. There always be one type can flash into your eyes. Participate in interaction, more surprises are waiting for you! Date: October 19 – 23, 2019 Booth：#D22，level 4 Address: China National Convention Center, Beijing, China About: The 17th International Congress of Immunology (IUIS 2019) will be held from October 19 – 23, 2019 at the China National Convention Center, Beijing, China. IUIS 2019 promises to be an unforgettable event that will bring together delegates from all over the world. We anticipate over 5000 participants, including international leaders at the forefront of the discipline that will present the most recent advances in…
In 4 years, Abbkine helped more than 1200 English articles to be published. Impact factors exceed 4500 points! ! !
Abbkine focuses on immunology and cytology, and is committed to innovating and developing various antibodies, proteins, analytical reagents and kits, with a view to becoming a key promoter in the fields of life science research and development, drug research and development, etc. Some articles published using Abbkine products: 1. The negative effect of silica nanoparticles on adipogenic differentiation of human mesenchymal stem cells. Materials Science and Engineering. (IF: 27.24) Using Abbkine Dylight 594, Goat Anti-Mouse IgG 2. Bph6 encodes an exocyst-localized protein and confers broad resistance to planthoppers in rice. NATURE GENETICS. (IF: 19.88) Using Abbkine Anti-Plant Actin Mouse Monoclonal Antibody (3T3) 3. The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis. . (IF: 19.14) Using Abbkine HRP, Goat Anti-Rabbit IgG 4.…
