KTE100650 | Rat Malondialdehyde (MDA) ELISA Kit — The Gold Standard for Lipid Peroxidation Quantification in Rat Models

MDA: The Definitive Marker of Oxidative Stress

Lipid peroxidation is one of the most damaging consequences of oxidative stress, and malondialdehyde (MDA) is its most widely measured end-product. When reactive oxygen species (ROS) attack polyunsaturated fatty acids in cellular membranes, a cascade of degradation reactions produces MDA—a highly reactive dialdehyde that cross-links proteins, DNA, and other biomolecules. In rat models of cardiovascular disease, neurodegeneration, liver injury, and diabetes, MDA is the biomarker that tells you whether oxidative damage is actually occurring.

Competitive ELISA: Precision Quantification of a Small-Molecule Marker

Unlike protein-based biomarkers, MDA is a small molecule that requires a competitive assay format for accurate quantification. KTE100650 employs the competitive enzyme immunoassay technique, where sample MDA competes with HRP-conjugated MDA for binding to a pre-coated antibody. The intensity of color development is inversely proportional to MDA concentration—the more MDA in your sample, the weaker the signal. This competitive format delivers exceptional sensitivity for low-molecular-weight analytes.

Rat-Specific, Oxidative-Stress Ready

With reactivity validated exclusively for Rat, this kit is specifically optimized for rat serum, plasma, tissue homogenates, and cell culture supernatants. Whether you're studying hepatic ischemia-reperfusion injury, diabetic nephropathy, or neuroinflammation, KTE100650 delivers MDA data you can trust.

Specifications

• Assay Type: Competitive ELISA (quantitative)
• Sample Types: Serum, Plasma, Tissue homogenates, Cell culture supernatants
• Assay Duration: 3–5 hours
• Storage: 2–8°C unopened
• Shipping: Gel pack with blue ice

Complete Kit Components

The kit includes: MDA microplate, MDA standards, HRP-conjugated MDA, detection antibody, substrate solutions, stop solution, wash buffer, and plate covers.

Who Needs This Kit?

• Cardiovascular researchers studying oxidative stress in heart disease
• Neuroscientists investigating neurodegeneration and neuroinflammation
• Hepatologists evaluating liver injury and fibrosis
• Diabetologists studying oxidative damage in metabolic disease
• Toxicologists assessing compound-induced oxidative stress

🔗 Reference Link: https://www.abbkine.com/product/rat-malondialdehyde-mda-elisa-kit-kte100650/