Descriptions:Bone morphogenetic protein -4 (BMP-4) is one of nine structurally related BMP's, belonging to transforming growth factor-β (TGF-β) superfamily, which secretes proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 treatment promoted the proliferation of HCC cells and induced autophagy. Mechanism study shows that autophagy induced by BMP-4 is mediated by activating JNK1/Bcl2 pathway. JNK1 inhibitor and JNK1 knockout can weaken BMP-4-induced autophagy and eliminate BMP-4-promoted HCC cell growth. BMP-4 promotes the proliferation of HCC through autophagy activation of JNK1/Bcl-2 signaling.
Tags:BMP-4
Descriptions:Granulocyte colony-stimulating factor(G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily.
Applications:His tag
Tags:G-CSF
Descriptions:Mouse Oncostatin M (OSM) Protein, expressed in E. coli
Tags:No-tag
Descriptions:This Rat 14-3-3 protein theta (YWHAQ) ELISA Kit employs a two-site sandwich ELISA to quantitate YWHAQ.
Reactivity:Rat
Applications:ELISA
Tags:YWHAQ
Descriptions:This Rat Tumor necrosis factor ligand superfamily member 15 (TNFSF15) ELISA Kit employs a two-site sandwich ELISA to quantitate TNFSF15.
Reactivity:Rat
Applications:ELISA
Tags:TNFSF15
Descriptions:This Human Protein Wnt-2 (WNT2) ELISA Kit employs a two-site sandwich ELISA to quantitate WNT2.
Reactivity:Human
Applications:ELISA
Tags:WNT2
Descriptions:This Human Thyroid Stimulating Hormone (TSH) ELISA Kit employs a two-site sandwich ELISA to quantitate TSH.
Reactivity:Human
Applications:ELISA
Tags:TSH
Descriptions:This Rat Thromboxane A2 (TXA2) ELISA Kit employs a two-site sandwich ELISA to quantitate TXA2.
Reactivity:Rat
Applications:ELISA
Tags:TXA2
Descriptions:Rat Glutathione (GSH) ELISA Kit employs a two-site sandwich ELISA to quantitate GSH in samples.
Reactivity:Rat
Applications:ELISA
Tags:GSH
Descriptions:This Human Vitamin C (VC) ELISA Kit employs a two-site sandwich ELISA to quantitate VC.
Reactivity:Human
Applications:ELISA
Tags:VC