Descriptions:Human FGF1/FGF acidic protein, expressed in E. coli
Tags:FGF1/aFGF
Descriptions:This Mouse Low density lipoprotein (LDL) ELISA Kit employs a two-site sandwich ELISA to quantitate LDL.
Reactivity:Mouse
Applications:ELISA
Tags:LDL
Descriptions:Human Human NT-3 Protein,expressed in E. coli
Tags:NT-3
Descriptions:Interleukin 25 (IL-25) is a cytokine with proinflammatory and anti-inflammatory effects, it predicts a molecular mass of 16.7 kDa. It can induce NF-κB activation, and stimulate the production of IL-8, which is the major chemotactic substance of neutrophils.
Tags:IL-25
Descriptions:白细胞介素-10 (IL-10),又称人类细胞因子合成抑制因子 (CSIF),是一种抗炎细胞因子。许多不同类型的细胞都能产生 IL-10,包括免疫细胞和非免疫细胞。IL-10 对树突状细胞 (DC) 和巨噬细胞具有抑制作用,是抗原呈递的强效抑制剂,并限制 Th1 相关细胞因子 IL-2 和干扰素-γ (IFN-γ) 的产生。IL-10 也是感染期间的关键免疫调节剂,因为它能够抑制炎症细胞因子的产生。因此,感染期间过度的 Th1 和 CD8+ T 细胞应答可能会受到抑制。
Tags:IL-10
Descriptions:血管内皮生长因子165 (VEGF165)是一种强效的生长和血管生成细胞因子,属于VEGF家族,包括VEGF-A、VEGF-B、VEGF-C、VEGF-D、VEGF-E和PIGF。VEGF165是一种丰富的糖基化细胞因子,由缺少相同的165个血管链组成。
Tags:VEGF165
Descriptions:Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has the function of promoting the synthesis of neurotransmitters and the growth of neurites in a specific neuronal population. Its action seems to be limited to the nervous system. Ciliary neurotrophic factor (CNTF) exerts its biological effects by activating a multi-subunit receptor complex consisting of an extracellular CNTF-binding subunit (CNTFα) and two transmembrane signaling proteins (glycoprotein gp130 and LIF receptor). CNTF is thought to be a potent survival factor in neurons and oligodendrocytes and may be associated with reduced tissue destruction during inflammatory episodes. CNTF is also a survival factor for peripheral sensory sympathetic ganglions and ciliary ganglia neurons. CNTF has been reported to have therapeutic potential and to greatly differentiate.
Tags:CNTF
Descriptions:Interleukin-1 alpha (IL1 alpha or IL1α) is a member of the interleukin-1 cytokine family, found constitutively present in epithelial layers of the entire gastrointestinal tract, lung, liver, kidney, endothelial cells, and astrocytes. The synthesized IL-1 alpha is a 31 kDa inactive precursor and can be cleaved by intracellular caspase-1 or extracellular proteases to generate the bioactive 17 kDa form and the 16 kDa N-terminal cleavage product. Both precursor and mature IL-1 alpha protein bind to the IL-1 receptor (IL-1R), initiating a cascade of inflammatory cytokines and chemokines production such as IL-6, IL-8, and TNF, in response to viral and bacterial pathogens conditions. IL-1 alpha plays a central role in immune-surveillance mechanisms, stimulating macrophages, neutrophils, and CD8+ T cells activity.
Applications:His tag
Tags:IL-1α
Descriptions:4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.
Applications:His tag
Tags:4-1BBL