KTE101106 | Rat Glutamate (Glu) ELISA Kit — The Excitatory Neurotransmitter, Quantified with Precision

Glutamate: The Brain's Primary Excitatory Neurotransmitter

Glutamate is the most abundant excitatory neurotransmitter in the mammalian central nervous system—responsible for the vast majority of fast excitatory synaptic transmission. Beyond its role in neurotransmission, glutamate is a key metabolite in the glutamate-glutamine cycle, linking neurotransmitter pools to energy metabolism and ammonia detoxification. Dysregulated glutamate signaling is implicated in excitotoxicity, ischemia, traumatic brain injury, and neurodegenerative diseases. In rat models, glutamate quantification is essential for neuroscience research.

Competitive ELISA: Designed for Small-Molecule Neurotransmitter Detection

As a small-molecule amino acid, glutamate requires a competitive assay format for accurate quantification. KTE101106 employs the competitive enzyme immunoassay technique, where sample glutamate competes with HRP-conjugated glutamate for binding to a pre-coated antibody. The intensity of color development is inversely proportional to glutamate concentration—the more glutamate in your sample, the weaker the signal.

Rat-Specific, Neuroscience-Research Ready

With reactivity validated exclusively for Rat, this kit is specifically optimized for rat serum, plasma, cerebrospinal fluid (CSF), brain tissue homogenates, and cell culture supernatants.

Specifications

• Assay Type: Competitive ELISA (quantitative)
• Sample Types: Serum, Plasma, Cerebrospinal fluid, Brain tissue homogenates, Cell culture supernatants
• Assay Duration: 3–5 hours
• Storage: 2–8°C unopened
• Shipping: Gel pack with blue ice

Complete Kit Components

The kit includes: Glutamate microplate, Glutamate standards, HRP-conjugated glutamate, detection antibody, substrate solutions, stop solution, wash buffer, and plate covers.

Who Needs This Kit?

• Neuroscientists studying excitotoxicity and neurodegeneration
• Psychiatrists investigating glutamate in psychiatric disorders
• Pharmacologists developing glutamate receptor modulators
• Stroke researchers studying ischemia and excitotoxicity
• Metabolic biologists investigating the glutamate-glutamine cycle

🔗 Reference Link: https://www.abbkine.com/product/rat-glutamate-glu-elisa-kit-kte101106/