EliKine™ Human IL-8 ELISA Kit — Application Scenarios for Inflammation and Cancer Research

IL-8: A Master Regulator of Inflammation and Angiogenesis

Interleukin 8 (IL-8) , also known as CXCL8, is a member of the CXC chemokine family[reference:107]. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types[reference:108]. It functions as a chemoattractant for neutrophils and other immune cells, and is also a potent angiogenic factor[reference:109]. IL-8 plays a role in the pathogenesis of bronchiolitis and other inflammatory diseases[reference:110].

Abbkine's EliKine™ Human IL-8 ELISA Kit (KTE6018) provides researchers with a sensitive, specific, and reliable tool for quantifying this critical chemokine in human samples. With 2 publications citing this kit[reference:111], it's a trusted tool in the research community. Here's how researchers across different fields are putting it to work.

Inflammation Research: Acute and Chronic Inflammation

IL-8 is a key mediator of neutrophil recruitment and inflammation. Inflammation researchers use this kit to:

• Quantify IL-8 levels in acute inflammatory models (infection, tissue injury)
• Monitor IL-8 in chronic inflammatory diseases (rheumatoid arthritis, inflammatory bowel disease, psoriasis)
• Assess the effects of anti-inflammatory compounds on IL-8 production
• Study the role of IL-8 in inflammatory signaling pathways

The sandwich ELISA format delivers quantitative data from serum, plasma, or cell culture supernatants[reference:112].

Cancer Research: Tumor Angiogenesis and Metastasis

IL-8 is a potent angiogenic factor that promotes tumor growth and metastasis[reference:113]. Oncology researchers leverage this kit to:

• Quantify IL-8 in cancer cell line conditioned media
• Monitor IL-8 levels in patient plasma/serum as a potential biomarker
• Study IL-8's role in tumor angiogenesis and vascularization
• Investigate IL-8 as a therapeutic target in cancer

High specificity ensures no cross-reactivity with other CXC chemokines — critical given the close homology within this chemokine family[reference:114].

Respiratory Research: Bronchiolitis and Lung Disease

IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection[reference:115]. Respiratory researchers use this kit to:

• Quantify IL-8 in bronchoalveolar lavage fluid and sputum
• Monitor IL-8 levels in viral respiratory infection models
• Study IL-8's role in asthma and COPD
• Assess the effects of anti-inflammatory therapies on IL-8 production

Infectious Disease Research: Host-Pathogen Interactions

IL-8 is a key mediator of the host inflammatory response to infection. Infectious disease researchers use this kit to:

• Monitor IL-8 levels in bacterial and viral infection models
• Study IL-8's role in neutrophil recruitment and pathogen clearance
• Assess vaccine-induced inflammatory responses
• Investigate IL-8 dysregulation in sepsis and septic shock

Why Choose This Kit for Your IL-8 Research?

Kit Components at a Glance

• Human IL-8 microplate
• Human IL-8 standard
• Human IL-8 detect antibody
• EliKine™ Streptavidin-HRP
• Standard diluent, assay buffer, HRP substrate, stop solution, wash buffer, plate covers[reference:118]

🔬 Which research field does your work belong to?
Inflammation Research | Cancer Biology | Respiratory Research | Infectious Disease | Other
Share your application with us — we'd love to hear how you're using this kit in your studies!

📌 Reference Link: EliKine™ Human IL-8 ELISA Kit — KTE6018