EliKine™ Human CRP ELISA Kit: A Critical Review for Inflammation Researchers

C-reactive protein (CRP) is an acute-phase protein belonging to the pentraxin family. Produced by the liver in response to inflammation, CRP levels in plasma increase dramatically during acute phase responses to tissue injury, infection, or other inflammatory stimuli. It's one of the most widely used clinical biomarkers for inflammation, infection, and cardiovascular risk assessment.

The EliKine™ Human CRP ELISA Kit (KTE6004) from Abbkine provides a sensitive, specific, and complete solution for quantifying CRP in human samples. Here's what you need to know before buying.

What's in the Box?

Everything you need—no additional reagents to purchase.

Advantages

1. Excellent Sensitivity

With a limit of detection of 8 pg/mL and a calibration range of 15.6–1000 pg/mL, this kit covers both normal and elevated CRP levels. The sub-picomolar sensitivity ensures detection even in samples with low-grade inflammation.

2. High Specificity

No significant cross-reactivity or interference between human CRP and analogues. Your CRP signal is clean and specific.

3. Broad Sample Compatibility

Validated for serum, plasma, cell culture supernatants, and other biological fluids—versatile for diverse experimental setups.

4. Published Validation

This kit has been cited in 1 publication—providing real-world confidence from the research community.

5. Biotin-Streptavidin Amplification

The biotin-conjugated detection antibody + Avidin-HRP system delivers signal amplification for enhanced sensitivity.

6. Complete Kit

All components included—no hidden costs or last-minute reagent sourcing.

7. Reliable Storage and Shipping

• Unopened kit: store at 2–8°C
• Shipped with gel pack and blue ice

Disadvantages

1. Human-Specific

This kit is specific to human CRP—not validated for mouse, rat, or other species.

2. Research Use Only

Not intended for human or clinical diagnosis. For clinical CRP testing, consider CLIA-certified assays.

3. Assay Duration

Standard sandwich ELISA with a working time of 3–5 hours.

4. Potential for High Sample Dilution

For samples with very high CRP levels (e.g., acute infection), dilution may be required to fall within the 15.6–1000 pg/mL range.

Who Should Buy This Kit?

✅ Buy this kit if you:

• Study inflammation, immunology, or infectious disease
• Need to quantify human CRP in serum, plasma, or cell culture
• Require high sensitivity (8 pg/mL LOD)
• Value specificity—no cross-reactivity with related proteins
• Want a complete, ready-to-use kit
• Appreciate biotin-streptavidin amplification for better signal
• Prefer a kit with published validation (1 citation)

❌ Consider alternatives if you:

• Need to detect mouse or rat CRP (check Abbkine's other offerings)
• Are working with clinical diagnostic samples
• Require a faster assay (<3 hours)
• Have samples with extremely high CRP levels (consider dilution or alternative platforms)

Quick Specs Summary

📌 Reference Link: EliKine™ Human CRP ELISA Kit — KTE6004