Dylight 488 Goat Anti-Rat IgG: The Green Channel Workhorse for Rat Model Research

Why Rat Models Demand Better Secondaries

Rat models are indispensable in neuroscience, toxicology, cardiovascular research, and immunology. When your primary antibodies are raised in rat, you need a secondary antibody that delivers consistent, bright, and specific signal—every time.

Abbkine's Dylight 488 Goat Anti-Rat IgG (A23240) is an affinity-purified polyclonal antibody targeting rat IgG whole molecules, with >95% purity confirmed by SDS-PAGE. Validated for FCM, ICC, and IF, with a recommended dilution of 1:50–1:1000. With 18 citations in the literature, A23240 has proven its reliability across diverse rat model research applications.

The Brightness Advantage

DyLight 488-antibody conjugates are brighter than Cy2 and FITC conjugates and comparable in brightness to Alexa Fluor 488 conjugates. This means you can detect low-abundance targets without compromising image quality.

Photostability: No More Fading Mid-Experiment

DyLight 488 conjugates exhibit less fading than FITC and Cy2 in mounting media, ensuring that your images remain crisp throughout long acquisition sessions. This is particularly important for confocal microscopy and multi-channel imaging.

Wide pH Tolerance

DyLight dyes remain fluorescent from pH 4 to pH 9—a critical advantage for experiments involving antigen retrieval, fixed tissues, or variable mounting conditions.

Specificity: Whole Molecule Rat IgG Recognition

A23240 reacts with whole molecule rat IgG, including heavy and light chains of rat immunoglobulins, with no reactivity on non-immunoglobulin serum proteins. It may cross-react with immunoglobulins from other species—a consideration for multiplexing experiments.

Product Specifications

📎 Reference: Dylight 488, Goat Anti-Rat IgG (A23240)