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Integrin α6 Polyclonal Antibody

Integrin α6 Polyclonal Antibody

Views(100) Publications(0) Catalog no(ABP53321)
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Specification

Product name Integrin α6 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Integrin α6
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background ITGA6 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
Gene ID 3655
Alternative ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f
Others Integrin α6 Polyclonal Antibody detects endogenous levels of Integrin α6 protein.
Accession P23229
Observed Band(KD) 125

Image & description

Fig.1. Western Blot analysis of NIH-3T3 cells using Integrin α6 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western Blot analysis of NIH-3T3 cells using Integrin α6 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Western Blot analysis of 3T3 cells using Integrin α6 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Western Blot analysis of 3T3 cells using Integrin α6 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

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