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Dsg2 Polyclonal Antibody

Dsg2 Polyclonal Antibody

Views(70) Publications(0) Catalog no(ABP54029)
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Specification

Product name Dsg2 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Dsg2 at AA rangle: 370-450
Host Rabbit
Reactivity Human
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Gene ID 1829
Alternative DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Others Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
Accession Q14126
Observed Band(KD) 140

Image & description

Fig. Western Blot analysis of Jurkat cells using Dsg2 Polyclonal Antibody.

Fig. Western Blot analysis of Jurkat cells using Dsg2 Polyclonal Antibody.

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