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CD6 Polyclonal Antibody

CD6 Polyclonal Antibody

Views(63) Publications(0) Catalog no(ABP53308)
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Specification

Product name CD6 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human CD6
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CD6; T-cell differentiation antigen CD6; T12; TP120; CD6

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CD6 encodes CD6 molecule found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID 923
Alternative CD6; T-cell differentiation antigen CD6; T12; TP120; CD6
Others CD6 Polyclonal Antibody detects endogenous levels of CD6 protein.
Accession P30203
Observed Band(KD) 73

Image & description

Fig.1. Western Blot analysis of 293 cells using CD6 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western Blot analysis of 293 cells using CD6 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100.

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