Descriptions：Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has the function of promoting the synthesis of neurotransmitters and the growth of neurites in a specific neuronal population. Its action seems to be limited to the nervous system. Ciliary neurotrophic factor (CNTF) exerts its biological effects by activating a multi-subunit receptor complex consisting of an extracellular CNTF-binding subunit (CNTFα) and two transmembrane signaling proteins (glycoprotein gp130 and LIF receptor). CNTF is thought to be a potent survival factor in neurons and oligodendrocytes and may be associated with reduced tissue destruction during inflammatory episodes. CNTF is also a survival factor for peripheral sensory sympathetic ganglions and ciliary ganglia neurons. CNTF has been reported to have therapeutic potential and to greatly differentiate.
Tags：CNTF
Descriptions：Interleukin-1 alpha (IL1 alpha or IL1α) is a member of the interleukin-1 cytokine family, found constitutively present in epithelial layers of the entire gastrointestinal tract, lung, liver, kidney, endothelial cells, and astrocytes. The synthesized IL-1 alpha is a 31 kDa inactive precursor and can be cleaved by intracellular caspase-1 or extracellular proteases to generate the bioactive 17 kDa form and the 16 kDa N-terminal cleavage product. Both precursor and mature IL-1 alpha protein bind to the IL-1 receptor (IL-1R), initiating a cascade of inflammatory cytokines and chemokines production such as IL-6, IL-8, and TNF, in response to viral and bacterial pathogens conditions. IL-1 alpha plays a central role in immune-surveillance mechanisms, stimulating macrophages, neutrophils, and CD8+ T cells activity.
Applications：His tag
Tags：IL-1α
Descriptions：4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.
Applications：His tag
Tags：4-1BBL
Descriptions：This Rat X-box-binding protein 1 (XBP1) ELISA Kit employs a two-site sandwich ELISA to quantitate XBP1.
Reactivity：Rat
Applications：ELISA
Tags：XBP1
Descriptions：This Rat Cardiac troponin C (cTn-C) ELISA Kit employs a two-site sandwich ELISA to quantitate cTn-C.
Reactivity：Rat
Applications：ELISA
Tags：cTn-C
Descriptions：This Human Proto-oncogene Wnt-1 (WNT1) ELISA Kit employs a two-site sandwich ELISA to quantitate WNT1.
Reactivity：Human
Applications：ELISA
Tags：WNT1
Descriptions：This Human TSC22 domain family protein 3 (TSC22D3) ELISA Kit employs a two-site sandwich ELISA to quantitate TSC22D3.
Reactivity：Human
Applications：ELISA
Tags：TSC22D3
Descriptions：This Rat Transthyretin (TTR) ELISA Kit employs a two-site sandwich ELISA to quantitate TTR.
Reactivity：Rat
Applications：ELISA
Tags：TTR
Descriptions：This Rat Corticotropin releasing hormone (CRH) ELISA Kit employs a two-site sandwich ELISA to quantitate CRH.
Reactivity：Rat
Applications：ELISA
Tags：CRH
