Descriptions:Fibroblast Growth Factors-19 (FGF-19) is mainly secreted from cholangiocytes, ductal cells. FGF-19 involved cell proliferation, glucose and bile acid metabolism via FGFR4 pathway
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Tags:His Tag
Descriptions:Nerve Growth Factors (NGF) is critical for the development and maintenance of the sympathetic and sensory neuron systems. NGF has been demonstrated as a complex that consists of three polypeptides named α, β and γ subunits. Among then, β subunit, which known as beta-NGF is a 26.9 kDa protein containing 241 residues that involve in neuronal survival and differentiation. Besides, beta-NGF also acts as a ligand to TRKA receptor, which indispensable for the differentiation and development of pain and temperature sensing neurons.
Applications:His tag
Tags:β-NGF
Descriptions:Insulin-like growth factor I(IGF1)belongs to a family of insulin-like growth factors with the same structure as proinsulin.Mature mouse IGF-I has 94% and 99% amino acid sequence identity with human and rat IGF-I,respectively,and shows cross-species activity.
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Tags:IGF-1
Descriptions:Bone Morphogenetic Protein-5 (BMP-5) is an extracellular multifunctional signaling cytokine that is also a member of the TGF-β family. BMP-5 can bind with TGF-β receptors and trigger SMAD protein signal transduction. It is involved in many negatively regulated physiological processes, such as the aldosterone biosynthetic process and epithelial to mesenchymal transition. BMP-5 also plays a vital role in cartilage synthesis.
Applications:His tag
Tags:BMP-5
Descriptions:Human TNF beta (Lymphotoxin-alpha) is a 22 kDa cytokine with 205 amino acid residues. TNF beta belongs to tumor necrosis factor (TNF) superfamily as TNF alpha. Binding to lymphotoxin-β receptor (LtβR), canonical and non-canonical NF-κB signal pathway will be activated. TNF beta is related to apoptosis and inflammatory signals
Applications:His tag
Tags:TNF-β
Descriptions:Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins. IL-9 is produced by variety of cells like mast cells, NKT cells, Th2, Th17, Treg, ILC2, and Th9 cells in different amounts. Among them, Th9 cells are regarded as the major CD4+ T cells that produce IL-9.
Applications:His tag
Tags:IL-9
Descriptions:Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-κB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.
Applications:His tag
Tags:IL-38
Descriptions:Mouse IL-10 is the prototypic member of the IL-10 cytokine family,including IL-10,IL-19,IL-20,IL-22(IL-TIF),IL-24 and IL-26.
Applications:No tag
Tags:IL-10