Descriptions:Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has the function of promoting the synthesis of neurotransmitters and the growth of neurites in a specific neuronal population. Its action seems to be limited to the nervous system. Ciliary neurotrophic factor (CNTF) exerts its biological effects by activating a multi-subunit receptor complex consisting of an extracellular CNTF-binding subunit (CNTFα) and two transmembrane signaling proteins (glycoprotein gp130 and LIF receptor). CNTF is thought to be a potent survival factor in neurons and oligodendrocytes and may be associated with reduced tissue destruction during inflammatory episodes. CNTF is also a survival factor for peripheral sensory sympathetic ganglions and ciliary ganglia neurons. CNTF has been reported to have therapeutic potential and to greatly differentiate.
Tags:CNTF
Descriptions:Mouse FGF-7 protein expressed in E. coli
Tags:FGF-7
Descriptions:Firefly Luciferase, Preparation method: E. coli
Tags:Firefly Luciferase
Descriptions:Mouse IL-1α protein expressed in E. coli
Tags:IL-1α
Descriptions:Human MMP2 (active) Protein, His tag (Animal-Free), expressed in E. coli
Tags:MMP2
Descriptions:Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological activities through specific cell surface receptors. The low affinity LIF receptor that shares the similarity of containing protein gp130 has now been identified to be a component of a high- affinity OSM receptor that will transduce OSM signals. OSM has also been shown to play a role in both pro and anti-inflammatory actions. OSM may also be involved in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development.
Tags:OSM
Descriptions:Mouse/Rat, TGF beta 1, His tag (Animal-Free), expressed in E. coli
Tags:TGF-β1
Descriptions:AREG is a one-way membrane protein consisting of 252 amino acids. AREG belongs to AREG family and contains an EGF-like domain. AREG is expressed in many tissues, including ovary, placenta, lung, kidney, stomach, colon and breast. It is related to epidermal growth factor (EGF) and transforming growth factor α (TGF-α). As an EGF-related growth factor, AREG interacts with EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibit the growth of some invasive cancer cell lines.
Tags:AREG
Descriptions:Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity.
Tags:CXCL1
Descriptions:Rat G-CSF Protein,expressed in E. coli
Tags:G-CSF