Descriptions:Tumor Necrosis Factor Beta (TNF beta) or lymphotoxin-alpha (LT-α) is a 19 kDa tumor necrosis factor family protein with 171 amino acid residues. TNF beta is mainly expressed from lymphocytes, and mediates variety of inflammatory, immunostimulatory, and antiviral responses. TNF beta also involves development in secondary lymphoid organs. It is cytotoxic for different tumor cells in vitro and in vivo.
Tags:TNF beta
Descriptions:C-X-C motif chemokine 4 (CXCL4) also named platelet factor 4 (PF4), which is a chemokine of the intercrine alpha family. CXCL4 is a 8kDa protein containing 70 amino acid residues. CXCL4 is produced by the activated platelets which plays an important role in immune responses. CXCL4 inhibit the cell proliferation, platelet aggregation and wound repair. CXCL4 also suppresses the hematopoiesis.
Applications:His tag
Tags:CXCL4
Descriptions:NAD-ME
Tags:NAD-ME
Descriptions:Haptoglobin is a glycoprotein, which is synthesized in the liver and circulates in the blood. Haptoglobin is usually produced by liver cells, but it is also produced by other tissues, such as skin, lung and kidney. It is a positive acute phase protein, which binds to free hemoglobin and removes it from circulation to prevent kidney injury and iron loss after hemolysis. Decreased levels can be seen in hemolysis and impaired liver function. A high level is a sign of acute or chronic inflammation. Hemoglobin deficiency or hypohaptoglobinemia is caused by mutation of haptoglobin gene and/or its regulatory region. Haptoglobin is also related to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, susceptibility to primary sclerosing cholangitis, idiopathic Parkinson's disease and the reduction of the incidence of plasmodium falciparum malaria.
Tags:Haptoglobin
Descriptions:Protopectin
Tags:Protopectin
Descriptions:C-X-C motif chemokine 3 (CXCL3) also named Growth-regulated oncogene gamma (GROγ), which is a chemokine of the intercrine alpha family. CXCL3 is a 8 kDa protein containing 73 amino acid residues. During inflammation, CXCL3 is activated by the TNF and IL-1 which mediates the monocytes migration and adhesion by targeting the CXCR2. CXCL3 activates the JNK activity which induce the cell differentiation.
Applications:His tag
Tags:CXCL3
Descriptions:Interleukin 9 (IL-9) is a pleiotropic cytokine that had pleiotropic functions in the immune system, has a molecular mass of 14.5 kDa. The major source of IL-9 is T lymphocytes. It is secreted by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells.
Tags:IL-9
Descriptions:Interleukin 1 receptor antagonist (IL-1RA) is a 17.26 kDa member of IL-1 family with 153 amino acid residues. IL-1RA is expressed by peripheral blood cells, lungs, spleen, liver and is secreted from monocytes, macrophages, neutrophils, and other cells. Inhibits the activity of interleukin-1 by binding to receptor IL1R1. IL-1RA can modulate a variety of interleukin-1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation.
Applications:His tag
Tags:IL-1RA
Descriptions:CHI
Tags:CHI