Descriptions:Human TGF-β1 protein, expressed in CHO Stable Cells
Tags:TGF-β1
Descriptions:This Mouse Matrix metalloproteinase 13 (MMP-13) ELISA Kit employs a two-site sandwich ELISA to quantitate MMP13.
Reactivity:Mouse
Applications:ELISA
Tags:MMP13
Descriptions:Human IFN-α2a Protein, expressed in E. coli
Tags:IFN-α2a
Descriptions:Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-κB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.
Tags:IL-38
Descriptions:The transforming Growth Factors beta (TGF beta) family of cytokines are ubiquitous, multifunctional, and essential to survival. They play the central roles in growth, development, inflammation, repair, and host immunity. The mammalian TGF beta isoforms (TGF beta 1, beta 2 and beta 3) are secreted as potential precursors and possess a variety of cell surface receptors and produces at least two mediate signal transductions.
Tags:TGF-β
Descriptions:Human IL-11 Protein, His tag (Animal-Free), expressed in E. coli
Tags:IL-11
Descriptions:R-spondin 1 (RSPO1, Roof plate-specific Spondin 1) is a cysteine-rich secreted glycoprotein that belongs to the R-Spondin family. Structurally, R-spondin 1 harbors an N-terminal signal peptide, two cysteine-rich furin-like (FU1-FU2) domains, a thrombospondin (TSP) domain, and a basic amino acid-rich (BR) C-terminal domain. R-spondin 1 acts as a ligand for the leucine-rich repeat-containing G-protein coupled receptor (LGR) family (LGR4/5/6), subsequent clearing negative regulators ZNRF3/RNF43 from the membrane, leading to the availability of Wnt receptor and activating Wnt/β-catenin signaling. The signal cascade is essential for regulating stem cell proliferation, embryonic development, and tissue homeostasis.
Applications:His-SUMO tag
Tags:RSPO1/R-spondin 1
Descriptions:核因子κB受体激活(RANK)配体(RANKL)是TNF细胞因子超家族中的镰基分裂,具有外结构域的II型跨膜蛋白。RANKL是一个核苷酸为19.8 kDa的蛋白质,含有3317个残基,在T细胞和显着T细胞的器官(如表达胸腺和肝脏)中高。RANKL-RANK(RANKL受体)在骨代谢、胶原蛋白和免疫系统中发挥重要作用。
Tags:RANKL
Descriptions:Human IL-23 p19 Protein, His tag (Animal-Free), expressed in E. coli
Tags:IL-23 p19
Descriptions:Interleukin 36 receptor antagonist (IL-36RA) is a 16.97 kDa member of IL-1 family with 155 amino acid residues. IL-1RA is expressed by lymphoid tissue, skin and secreted to blood. IL-36Ra functions as a receptor antagonist that inhibits the activation of IL-36R signaling and suppresses pro-inflammatory signaling.
Applications:His tag
Tags:IL-36RA