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ZnT-8 Polyclonal Antibody

ZnT-8 Polyclonal Antibody

Views(55) Publications(0) Catalog no(ABP53994)
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Specification

Product name ZnT-8 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human ZnT-8 at AA rangle: 140-220
Host Rabbit
Reactivity Human
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Zinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.
Gene ID 169026
Alternative SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
Others ZnT-8 Polyclonal Antibody detects endogenous levels of ZnT-8 protein.
Accession Q8IWU4
Observed Band(KD) 41

Image & description

Fig. Western Blot analysis of K562 cells using ZnT-8 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig. Western Blot analysis of K562 cells using ZnT-8 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

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