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SYT14 Polyclonal Antibody

SYT14 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP60572)
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Specification

Product name SYT14 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human SYT14 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Synaptotagmin-14; Synaptotagmin XIV; SytXIV

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 61kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background SYT14 (Synaptotagmin 14) is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in SYT14 are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of SYT14 is located on the long arm of chromosome 4.
Gene ID 255928
Alternative Synaptotagmin-14; Synaptotagmin XIV; SytXIV
Others The antibody detects endogenous levels of SYT14 protein
Accession Q8NB59
Observed Band(KD) 61

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