| Product name | POT1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human POT1 |
| Host | Rabbit |
| Reactivity | Human,Monkey |
| Applications | WB,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 70kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression. |
| Gene ID | 25913 |
| Alternative | POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein |
| Others | POT1 Polyclonal Antibody detects endogenous levels of POT1 protein. |
| Accession | Q9NUX5 |
| Observed Band(KD) | 70 |
Fig. Western Blot analysis of various cells using POT1 Polyclonal Antibody.
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