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Cleaved-Ephrin-A2 (N188) Polyclonal Antibody

Cleaved-Ephrin-A2 (N188) Polyclonal Antibody

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Specification

Product name Cleaved-Ephrin-A2 (N188) Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human Ephrin-A2 at AA range: 110-190
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative EFNA2; EPLG6; LERK6; Ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background EFNA2 encodes a member of the ephrin family. Ephrin A2 is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether ephrin A2 localizes to the nucleus or the cytoplasm.
Gene ID 1943
Alternative EFNA2; EPLG6; LERK6; Ephrin-A2; EPH-related receptor tyrosine kinase ligand 6; LERK-6; HEK7 ligand; HEK7-L
Others Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.
Accession O43921
Observed Band(KD) 21

Image & description

Fig. Western Blot analysis of various cells using Cleaved-Ephrin-A2 (N188) Polyclonal Antibody.

Fig. Western Blot analysis of various cells using Cleaved-Ephrin-A2 (N188) Polyclonal Antibody.

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