| Product name | Plakophilin 2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Plakophilin 2 at AA range: 610-690 |
| Host | Rabbit |
| Reactivity | Human,Rat |
| Applications | WB,ELISA,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | PKP2; Plakophilin-2 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 97kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | PKP2 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. |
| Gene ID | 5318 |
| Alternative | PKP2; Plakophilin-2 |
| Others | Plakophilin 2 Polyclonal Antibody detects endogenous levels of Plakophilin 2 protein. |
| Accession | Q99959 |
| Observed Band(KD) | 97 |
Fig.1. Western Blot analysis of various cells using Plakophilin 2 Polyclonal Antibody diluted at 1:500.
Fig.2. Western Blot analysis of HepG2 cells using Plakophilin 2 Polyclonal Antibody diluted at 1:500.
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