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PFK-2 liv Polyclonal Antibody

PFK-2 liv Polyclonal Antibody

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Specification

Product name PFK-2 liv Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human PFK-2 liv at AA range: 380-460
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for PFKFB1.
Gene ID 5207
Alternative PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2,6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2,6-P2ase liver isozyme
Others PFK-2 liv Polyclonal Antibody detects endogenous levels of PFK-2 liv protein.
Accession P16118
Observed Band(KD) 58

Image & description

Fig.1. Western Blot analysis of various cells using PFK-2 liv Polyclonal Antibody.

Fig.1. Western Blot analysis of various cells using PFK-2 liv Polyclonal Antibody.

Fig.2. Western Blot analysis of Jurkat cells using PFK-2 liv Polyclonal Antibody.

Fig.2. Western Blot analysis of Jurkat cells using PFK-2 liv Polyclonal Antibody.

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