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OB-cadherin Polyclonal Antibody

OB-cadherin Polyclonal Antibody

Views(60) Publications(0) Catalog no(ABP53423)
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Specification

Product name OB-cadherin Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human OB-cadherin at AA rangle: 390-470
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CDH11 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Gene ID 1009
Alternative CDH11; Cadherin-11; OSF-4; Osteoblast cadherin; OB-cadherin
Others OB-cadherin Polyclonal Antibody detects endogenous levels of OB-cadherin protein.
Accession P55287
Observed Band(KD) 85

Image & description

Fig. Western Blot analysis of Jurkat cells using OB-cadherin Polyclonal Antibody.

Fig. Western Blot analysis of Jurkat cells using OB-cadherin Polyclonal Antibody.

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