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c-Rel (phospho Ser503) Polyclonal Antibody

c-Rel (phospho Ser503) Polyclonal Antibody

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Product name c-Rel (phospho Ser503) Polyclonal Antibody
Immunogen Synthesized peptide derived from human c-Rel around the phosphorylation site of S503
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative REL; Proto-oncogene c-Rel

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background REL (REL proto-oncogene, NF-kB subunit) encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of REL is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in REL are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID 5966
Alternative REL; Proto-oncogene c-Rel
Others Phospho-c-Rel (S503) Polyclonal Antibody detects endogenous levels of c-Rel protein only when phosphorylated at S503.
Accession Q04864

Image & description

Fig. Western Blot analysis of 3T3 cells using Phospho-c-Rel (S503) Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of 3T3 cells using Phospho-c-Rel (S503) Polyclonal Antibody diluted at 1:1000.

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