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Neurofibromin Polyclonal Antibody

Neurofibromin Polyclonal Antibody

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Specification

Product name Neurofibromin Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Neurofibromin at AA range: 1520-1600
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative NF1; Neurofibromin; Neurofibromatosis-related protein NF-1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
Gene ID 4763
Alternative NF1; Neurofibromin; Neurofibromatosis-related protein NF-1
Others Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
Accession P21359
Observed Band(KD) 319

Image & description

Fig.1. Western Blot analysis of various cells using Neurofibromin Polyclonal Antibody.

Fig.1. Western Blot analysis of various cells using Neurofibromin Polyclonal Antibody.

Fig.2. Western Blot analysis of HepG2 cells using Neurofibromin Polyclonal Antibody.

Fig.2. Western Blot analysis of HepG2 cells using Neurofibromin Polyclonal Antibody.

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