| Product name | IL-31 Polyclonal Antibody |
| Immunogen | Synthetic peptide from human protein at AA range: 21-70 |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Interleukin-31; IL-31 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | IL31 (interleukin 31), which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. |
| Gene ID | 386653 |
| Alternative | Interleukin-31; IL-31 |
| Others | The antibody detects endogenous IL-31. |
| Accession | Q6EBC2 |
| Observed Band(KD) | 65 |
Fig.1. Western blot analysis of Hela Cell Lysate using antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.
Fig.4. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:200.
Fig.5. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:200.
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