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HXB3 Polyclonal Antibody

HXB3 Polyclonal Antibody

Views(5) Publications(0) Catalog no(ABP58837)
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Specification

Product name HXB3 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human HXB3 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Homeobox protein Hox-B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 47kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background HOXB3 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of HOXB3 is associated with a distinct biologic subset of acute myeloid leukemia (AML). HOXB3 (Homeobox B3) is a Protein Coding gene. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Developmental Biology.
Gene ID 3213
Alternative Homeobox protein Hox-B3; Homeobox protein Hox-2.7; Homeobox protein Hox-2G
Others The antibody detects endogenous levels of HXB3 protein
Accession P14651
Observed Band(KD) 47

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