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Glut3 Polyclonal Antibody

Glut3 Polyclonal Antibody

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Specification

Product name Glut3 Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human Glut3 at AA range: 420-500
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative SLC2A3; GLUT3; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GLUT3 (SLC2A3) belongs to the glucose transporter family (GLUTs) which mediates the transport of glucose across cellular membranes in mammalian cells. There are three subclasses within GLUTs: class I comprises the classical transporters GLUT1-4 and GLUT14; class II contains the "odd" isoforms GLUT5, 7, 9, and 11; the isoforms GLUT6, 8, 10, 12 and the proton driven myoinositol transporter HMIT (GLUT13) belong to class III. GLUT3 is considered as a neuron-specific glucose transporter because of its dominant expression in the brain in various species. However, besides the brain GLUT3 is also expressed in tissues with high demand for glucose such as sperm, preimplantation embryos, circulating white blood cells, and an array of carcinoma cell lines. ecently GLUT3 has been identified as a sensitive and specific marker for embyonal carcinomas and yolk tumors. he GLUT14 is believed to be the duplicate gene of GLUT3 given to the high identity in sequence between them. This antibody was generated against the internal region of human GLUT3 and may cross-react with GLUT14.
Gene ID 6515
Alternative SLC2A3; GLUT3; Solute carrier family 2; facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3
Others Glut3 Polyclonal Antibody detects endogenous levels of Glut3 protein.
Accession P11169
Observed Band(KD) 55

Image & description

Fig.1. Western Blot analysis of SH-SY5Y cells using Glut3 Polyclonal Antibody diluted at 1:2000.

Fig.1. Western Blot analysis of SH-SY5Y cells using Glut3 Polyclonal Antibody diluted at 1:2000.

Fig.2. Western blot analysis of Mouse-kidney lysis using Glut3 antibody. Antibody was diluted at 1:2000.

Fig.2. Western blot analysis of Mouse-kidney lysis using Glut3 antibody. Antibody was diluted at 1:2000.

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