| Product name | Human/Mouse/Rat TGF β1 protein, His tag |
| Sequence | Amino acid sequence derived from Human/Mouse/Rat TGF-β1 (P01137) (Ala279-Ser390) was expressed with 6×His tag at N-terminus. |
| Applications | His tag |
| Applications notes | Human |
| Activity | Testing in progress |
| Protein length | The recombinant Human IL-1α Protein consists of 159 amino acids and predicts a molecular mass of 19 kDa. |
| Preparation method | E.coli |
| Purity | > 95 % as determined by SDS-PAGE |
| Molecular Formula | 12.9 kDa |
| Alternative | TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta |
| Formulation | Lyophilized from sterile PBS，pH 5.0. |
| Features & Benefits | <0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 12.9 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | TGF-β1 is a member of transforming growth factor β(TGF-β) family. Transforming growth factor-β polypeptide family is involved in the regulation of cell processes, including cell division, differentiation, movement, adhesion and death. TGF-β1 regulates many other growth factors positively and negatively. It inhibits the secretion and activity of many other cytokines, including interferon-γ, tumor necrosis factor-α and various interleukins. It can also reduce the expression level of cytokine receptor. TGF-β1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling, because it is an effective stimulator of osteoblast bone formation, causing the chemotaxis, proliferation and differentiation of directional osteoblasts. Once cells lose their sensitivity to TGF-β1-mediated growth inhibition, autocrine TGF-β signal will promote tumor occurrence. |
| Gene ID | 7040 |
| Alternative | TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta |
| Accession | P01137 |
Author：Y Pan, D Zhang, J Zhang, X Liu, J Xu Publication name：Allergy, Asthma & Immunology Research IF：4.4
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