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GUC2B Polyclonal Antibody

GUC2B Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP58735)
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Specification

Product name GUC2B Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human GUC2B protein
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Guanylate cyclase activator 2B; Guanylate cyclase C-activating peptide 2; Guanylate cyclase C-activating peptide II; GCAP-II; UGN

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 12kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GUCA2B encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. GUCA2B (Guanylate Cyclase Activator 2B) is a Protein Coding gene. Diseases associated with GUCA2B include Colorectal Cancer. Among its related pathways are Metabolism and Miscellaneous digestion events.
Gene ID 2981
Alternative Guanylate cyclase activator 2B; Guanylate cyclase C-activating peptide 2; Guanylate cyclase C-activating peptide II; GCAP-II; UGN
Others The antibody detects endogenous levels of GUC2B protein
Accession Q16661
Observed Band(KD) 12

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