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GBP5 Polyclonal Antibody

GBP5 Polyclonal Antibody

Views(66) Publications(0) Catalog no(ABP53657)
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Specification

Product name GBP5 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human GBP5
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative GBP5; Guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include chronic active epstein-barr virus infection. Among its related pathways are Immune System and Interferon gamma signaling. GO annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP7. s an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed: 22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed: 20180847).
Gene ID 115362
Alternative GBP5; Guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; GBP-5; Guanine nucleotide-binding protein 5
Others GBP5 Polyclonal Antibody detects endogenous levels of GBP5 protein.
Accession Q96PP8
Observed Band(KD) 66

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