| Product name | Fascin 1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human Fascin 1 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 55kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | FSCN1 encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The fascin actin-bundling protein 1 plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. |
| Gene ID | 6624 |
| Alternative | FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55 |
| Others | Fascin 1 Polyclonal Antibody detects endogenous levels of Fascin 1 protein. |
| Accession | Q16658 |
| Observed Band(KD) | 55 |
Fig.1. Western Blot analysis of A549, HUVEC, HT29, K562, L929 cells using Fascin 1 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100.
Fig.3. Immunohistochemical analysis of paraffin-embedded Mouse-brain, antibody was diluted at 1:100.
Fig.4. Immunohistochemical analysis of paraffin-embedded Mouse-brain, antibody was diluted at 1:100.
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