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CNPase Polyclonal Antibody

CNPase Polyclonal Antibody

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Specification

Product name CNPase Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human CNPase
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CNP; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.
Gene ID 1267
Alternative CNP; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase
Others CNPase Polyclonal Antibody detects endogenous levels of CNPase protein.
Accession P09543
Observed Band(KD) 47

Image & description

Fig.1. Western Blot analysis of various cells using CNPase Polyclonal Antibody diluted at 1:500.

Fig.1. Western Blot analysis of various cells using CNPase Polyclonal Antibody diluted at 1:500.

Fig.2. Western Blot analysis of MCF7 cells using CNPase Polyclonal Antibody diluted at 1:500.

Fig.2. Western Blot analysis of MCF7 cells using CNPase Polyclonal Antibody diluted at 1:500.

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