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Claudin-5 (phospho Tyr217) Polyclonal Antibody

Claudin-5 (phospho Tyr217) Polyclonal Antibody

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Specification

Product name Claudin-5 (phospho Tyr217) Polyclonal Antibody
Immunogen Synthesized peptide derived from human Claudin-5 around the phosphorylation site of Y217
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CLDN5 (claudin 5) encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in CLDN5 have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for CLDN5.
Gene ID 7122
Alternative CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF
Others Phospho-Claudin-5 (Y217) Polyclonal Antibody detects endogenous levels of Claudin-5 protein only when phosphorylated at Y217.
Accession O00501
Observed Band(KD) 23

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