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CD85c Polyclonal Antibody

CD85c Polyclonal Antibody

Views(63) Publications(0) Catalog no(ABP53241)
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Specification

Product name CD85c Polyclonal Antibody
Immunogen Synthesized peptide derived from the N-terminal region of human CD85c
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background LILRB5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B5 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID 10990
Alternative LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c
Others CD85c Polyclonal Antibody detects endogenous levels of CD85c protein.
Accession O75023
Observed Band(KD) 65

Image & description

Fig.1. Western Blot analysis of HepG2 cells using CD85c Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western Blot analysis of HepG2 cells using CD85c Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100.

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