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Cathepsin D Polyclonal Antibody

Cathepsin D Polyclonal Antibody

Views(48) Publications(0) Catalog no(ABP53899)
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Specification

Product name Cathepsin D Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Cathepsin D
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CTSD; CPSD; Cathepsin D

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
Gene ID 1509
Alternative CTSD; CPSD; Cathepsin D
Others Cathepsin D Polyclonal Antibody detects endogenous levels of Cathepsin D protein.
Accession P07339
Observed Band(KD) 44

Image & description

Fig. Western Blot analysis of HeLa cells using Cathepsin D Polyclonal Antibody.

Fig. Western Blot analysis of HeLa cells using Cathepsin D Polyclonal Antibody.

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