| Product name | Calcein AM |
| CAS Number | 148504-34-1 |
| Molecular Formula | C46H46N2O23 |
| Alternative | Calcein AM,BMD00064 |
| Formulation | Gray solid |
| Features & Benefits | • λEX/λEm: 494/517 nm (pH 8) (calcein) |
| Molecular weight | 995 |
| Usage notes | • Soluble in DMSO |
| Storage instructions | Store at -20°C. The product can be stored for up to 12 months. Protect from light. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein, a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell communication, cytotoxicity, or changes in intracellular calcium, fluoride, iron, or mercury. As calcein is a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3), calcein AM is used to study these proteins and their regulation. |
| Alternative | Calcein AM,BMD00064 |
Fig. Calcein AM structure formula
Author：Y Cao, P Cheng, S Sang, C Xiang, Y An Publication name：Regenerative Biomaterials IF：6.535
Author：Yuling Tong, Liping Liu, Ruilin Wang Publication name：Front Pharmacol IF：4.225
Author：Tong Y, Wang R, Liu X, Tian M, Wang Y, Cui Y, Zou W, Zhao Y Publication name：Journal of IF：3.69
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