|Product name||Calcein AM|
|Features & Benefits||• λEX/λEm: 494/517 nm (pH 8) (calcein)|
|Usage notes||• Soluble in DMSO|
|Storage instructions||Store at -20°C. The product can be stored for up to 12 months. Protect from light.|
|Shipping||Gel pack with blue ice.|
|Precautions||The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.|
|Background||Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein, a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell communication, cytotoxicity, or changes in intracellular calcium, fluoride, iron, or mercury. As calcein is a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3), calcein AM is used to study these proteins and their regulation.|
Fig. Calcein AM structure formula
Author：Y Cao, P Cheng, S Sang, C Xiang, Y An Publication name：Regenerative Biomaterials IF：6.535
Author：Yuling Tong, Liping Liu, Ruilin Wang Publication name：Front Pharmacol IF：4.225
Author：Tong Y, Wang R, Liu X, Tian M, Wang Y, Cui Y, Zou W, Zhao Y Publication name：Journal of IF：3.69
1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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