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Cadherin-23 Polyclonal Antibody

Cadherin-23 Polyclonal Antibody

Views(96) Publications(0) Catalog no(ABP56148)
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Specification

Product name Cadherin-23 Polyclonal Antibody
Immunogen Synthesized peptide derived from the N-terminal region of human Cadherin-23 at AA range: 30-110
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of CDH23 may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.
Gene ID 64072
Alternative CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin
Others Cadherin-23 Polyclonal Antibody detects endogenous levels of Cadherin-23 protein.
Accession Q9H251

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