| Product name | BCoR Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human BCoR at AA range: 1200-1280 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | BCOR; KIAA1575; BCL-6 corepressor; BCoR |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 192kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein (BCL6 corepressor) encoded by BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for BCOR. A pseudogene of this gene is found on chromosome Y. |
| Gene ID | 54880 |
| Alternative | BCOR; KIAA1575; BCL-6 corepressor; BCoR |
| Others | BCoR Polyclonal Antibody detects endogenous levels of BCoR protein. |
| Accession | Q6W2J9 |
Fig. Western Blot analysis of various cells using BCoR Polyclonal Antibody diluted at 1:500.
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