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APRIL Polyclonal Antibody

APRIL Polyclonal Antibody

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Specification

Product name APRIL Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human APRIL at AA range: 120-200
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative TNFSF13; APRIL; TALL2; ZTNF2; Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD antigen CD256

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein (tumor necrosis factor superfamily member 13) is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of TNFSF13 have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Gene ID 8741
Alternative TNFSF13; APRIL; TALL2; ZTNF2; Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD antigen CD256
Others APRIL Polyclonal Antibody detects endogenous levels of APRIL protein.
Accession O75888

Image & description

Fig.1. Western Blot analysis of various cells using APRIL Polyclonal Antibody diluted at 1:2000.

Fig.1. Western Blot analysis of various cells using APRIL Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of COLO205 cells using APRIL Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of COLO205 cells using APRIL Polyclonal Antibody diluted at 1:2000.

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