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APLP-2 Polyclonal Antibody

APLP-2 Polyclonal Antibody

Views(65) Publications(0) Catalog no(ABP50680)
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Specification

Product name APLP-2 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human APLP-2 at AA range: 210-290
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative APLP2; APPL2; Amyloid-like protein 2; APLP-2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background APLP2 encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID 334
Alternative APLP2; APPL2; Amyloid-like protein 2; APLP-2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP
Others APLP-2 Polyclonal Antibody detects endogenous levels of APLP-2 protein.
Accession Q06481

Image & description

Fig.1. Western Blot analysis of various cells using APLP-2 Polyclonal Antibody diluted at 1:2000.

Fig.1. Western Blot analysis of various cells using APLP-2 Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of 3T3 cells using APLP-2 Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of 3T3 cells using APLP-2 Polyclonal Antibody diluted at 1:2000.

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