| Product name | Acetyl NF kB P65 (K314/K315) Mouse Monoclonal Antibody (2A11) |
| Immunogen | Synthetic Peptide of Acetyl NF kB P65 (K314/K315) |
| Host | Mouse |
| Reactivity | Human,Mouse,Rat |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200 |
| Clonality | Monoclonal |
| Preparation method | The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 65kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA (RELA proto-oncogene, NF-kB subunit), or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of RELA, RELA. Four transcript variants encoding different isoforms have been found for RELA. |
| Gene ID | 5970 |
| Alternative | Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 |
| Others | The antibody detects endogenous Acetyl NF kB P65 (K314/K315) protein. |
| Accession | Q04206 |
Fig.1. Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Acetyl NF kB P65 (K314/K315) Mouse mAb diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Acetyl NF kB P65 (K314/K315) Mouse mAb diluted at 1:200.
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